Description

1,2-Di4,7,10,13,16,19 (All-Cis) Docosahexaenoyl-Sn-Glycero-3-Phosphocholine is a highly purified, synthetic phospholipid where both sn-1 and sn-2 positions are esterified with docosahexaenoic acid (DHA). This compound is critical for advanced research and development in lipid-based drug delivery systems due to its role in mimicking and constructing specialized cell membranes. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and manufacturers of high-value nutraceuticals and liposomal formulations.

Application

• Liposomal Drug Delivery: A key structural component for creating stable, targeted liposomes for encapsulating therapeutic agents.
• Biomembrane Research: Used in model membrane studies to investigate the biophysical properties and functions of DHA-rich phospholipids.
• Nutraceutical Formulations: Incorporated into high-end dietary supplements aimed at supporting brain and ocular health.
• Pharmaceutical Excipient: Serves as a functional excipient in advanced parenteral formulations requiring enhanced biocompatibility.
• Biochemical Reagent: Employed as a standard or substrate in enzymatic assays and metabolic pathway studies.
• Cosmeceutical Applications: Used in premium skincare products for its potential membrane-stabilizing and protective properties.

Basic Information

Item	Details
Product Name	1,2-Di4,7,10,13,16,19 (All-Cis) Docosahexaenoyl-Sn-Glycero-3-Phosphocholine
CAS No.	99296-81-8
Molecular Formula	C56H88NO8P
Molecular Weight	934.27 g/mol
Synonyms	1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine; DHA-PC; 1,2-di-DHA-PC; 1,2-Di-DHA Phosphatidylcholine; PC(22:6/22:6); 3-sn-Phosphatidylcholine, 1,2-di-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-; 1,2-Di(22:6) PC
EINECS	Contact for details

Quality Control

Every batch of our 1,2-Di-DHA Phosphatidylcholine is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, fatty acid profile, and solvent residues is provided with each shipment. Our quality commitment aligns with cGMP principles for pharmaceutical-grade materials.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The material is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a desiccator before opening to avoid condensation.

Specification

Item	Specification
Appearance	Yellowish viscous liquid or solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Assay (Phosphorus Content)	≥ 98% of theoretical
Fatty Acid Composition (GC)	DHA ≥ 98% of total fatty acids
Solvent Residues (GC)	Meets ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.