Description

n-(4-Iodoazidosalicyl)-6-Amido-6-Deoxyglucopyranose is a specialized photoaffinity labeling reagent designed for covalent cross-linking studies in biochemistry and molecular biology. This compound matters for its unique bifunctional design, incorporating a photoreactive azido group and a carbohydrate moiety, enabling the study of carbohydrate-protein interactions and receptor mapping. It is primarily needed by research scientists and pharmaceutical developers working in proteomics, glycomics, and drug discovery for target identification and validation.

Application

• Photoaffinity Labeling: Covalent tagging of carbohydrate-binding proteins, lectins, and receptors for isolation and identification.
• Glycoprotein Research: Probing the structure and function of glycoproteins and their interaction networks.
• Drug Discovery: Target validation and mechanism-of-action studies for therapeutics targeting carbohydrate-mediated processes.
• Bioconjugation & Probe Development: Serving as a key intermediate for synthesizing advanced biochemical probes and diagnostic tools.
• Enzyme Inhibition Studies: Investigating the active sites of glycosidases and other carbohydrate-processing enzymes.
• Material Science: Surface functionalization of materials for biosensor development and biomimetic interfaces.

Basic Information

Product Name	n-(4-Iodoazidosalicyl)-6-Amido-6-Deoxyglucopyranose
CAS No.	98897-10-0
Molecular Formula	C13H14IN3O7
Molecular Weight	451.17 g/mol
Synonyms	6-Deoxy-6-[[(2-hydroxy-5-iodo-3-azidophenyl)carbonyl]amino]-D-glucopyranose; 6-[[(5-Iodo-2-hydroxy-3-azidobenzoyl)amino]-6-deoxy-D-glucopyranose; N-(5-Iodo-2-hydroxy-3-azidobenzoyl)-6-amino-6-deoxy-D-glucopyranose; Iodoazidosalicylamido-deoxyglucose; IASG; Photoaffinity Glucose Analog; Carbohydrate-Based Photoaffinity Probe
EINECS	Contact for details

Quality Control

Our n-(4-Iodoazidosalicyl)-6-Amido-6-Deoxyglucopyranose is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, critical for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and spectroscopic methods for structural confirmation. Certificates of Analysis (COA) with detailed specifications are provided to guarantee compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and degradation. Allow the container to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.