Description

22-o-Methylmycotrienin Ii CAS NO 98873-82-6 is a specialized ansamycin-class compound, a semi-synthetic derivative of the natural mycotrienin antibiotics. This compound is valued for its potent biological activity, serving as a critical intermediate and reference standard in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies focused on developing novel anti-infective and anti-tubercular agents, as well as in biochemical studies targeting bacterial RNA polymerase.

Application

• Pharmaceutical R&D Intermediate: A key building block in the synthesis of next-generation ansamycin antibiotics.
• Biochemical Research: Used as a potent inhibitor in studies of bacterial transcription, specifically targeting RNA polymerase.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Anti-Tubercular Agent Development: Investigated for its activity against *Mycobacterium tuberculosis* and related strains in drug discovery programs.
• Microbiological Studies: Employed in research to understand structure-activity relationships (SAR) within the ansamycin family.
• Academic Research: Utilized in university and institutional labs for studies in medicinal chemistry and molecular pharmacology.

Basic Information

Product Name	22-o-Methylmycotrienin Ii
CAS No.	98873-82-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	22-O-Methylmycotrienin II; Mycotrienin II, 22-O-methyl-; 22-O-Methyl-mycotrienin II; Ansamycin derivative; Rifamycin analog; TMC-207 related compound; Antibiotic SL 2266 derivative
EINECS	Contact for details

Quality Control

Our 22-o-Methylmycotrienin Ii is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry guidelines for reference standards and can provide material suitable for use in regulated environments upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability. Keep the container tightly sealed in a dry, cool, and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in DMSO, Methanol; Slightly soluble in Water
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.