Description

4-o-[2-(Dipropylamino)-2-Oxoethyl]Rifamycin is a semi-synthetic derivative of the rifamycin class of antibiotics, known for its potent antibacterial activity. This compound is a key intermediate in the synthesis of advanced antimicrobial agents, offering significant value in pharmaceutical research and development. It is primarily utilized by pharmaceutical manufacturers and research institutions focused on developing novel treatments for bacterial infections, particularly those targeting Gram-positive bacteria and tuberculosis.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of next-generation rifamycin-based antibiotics.
• Antimicrobial Research: Used in biochemical and microbiological research to study structure-activity relationships and mechanisms of action against bacterial RNA polymerase.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the development and scale-up of new antibacterial drug candidates.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Veterinary Medicine: Potential use in the development of antibacterial treatments for veterinary applications.

Basic Information

Product Name	4-o-[2-(Dipropylamino)-2-Oxoethyl]Rifamycin
CAS No.	16784-03-5
Molecular Formula	C39H53N3O13
Molecular Weight	771.85 g/mol
Synonyms	Rifamycin Derivative; 4-O-[2-(Dipropylamino)-2-oxoethyl]rifamycin; Rifampicin intermediate; 3-[[(4-Methyl-1-piperazinyl)imino]methyl]rifamycin; Rifamycin SV derivative; Antibiotic AF/ABDP; (2S,12Z,14E,16S,17S,18R,19R,20R,21S,22R,23S,24E)-21-Acetoxy-6,9,17,19-tetrahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,2-dihydro-2,7-(epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-1,11(2H)-dione 25-[2-(Dipropylamino)-2-oxoethyl] ether
EINECS	Contact for details

Quality Control

Our 4-o-[2-(Dipropylamino)-2-Oxoethyl]Rifamycin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR for identification, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical intermediates. Certificates of Analysis (COA) are provided with every shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Reddish-brown to orange powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.