Description

Rifamycin Sv CAS NO 15105-92-7 is a semisynthetic antibiotic belonging to the ansamycin class, derived from the natural product rifamycin B. This compound is valued for its potent antibacterial activity, particularly against Gram-positive bacteria and mycobacteria. It serves as a critical intermediate in the synthesis of more complex rifamycin derivatives and is essential for manufacturers in the pharmaceutical, research, and fine chemical sectors requiring high-purity antibiotic building blocks.

Application

• Pharmaceutical Intermediate: Primary use as a key precursor in the synthesis of advanced rifamycin antibiotics like rifampicin and rifabutin.
• Antibacterial Research: Used in microbiological and biochemical research to study bacterial RNA polymerase inhibition and antibiotic resistance mechanisms.
• Veterinary Medicine: Employed in the development of antibacterial treatments for veterinary applications.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical laboratories.
• Fine Chemical Synthesis: Utilized in custom synthesis and the production of specialized chemical entities for experimental purposes.

Basic Information

Product Name	Rifamycin Sv
CAS No.	15105-92-7
Molecular Formula	C37H47NO12
Molecular Weight	697.77 g/mol
Synonyms	Rifamycin S.V.; Rifamycin SV; Rifamycin 5; Rifocin; Rifamycin S Veta; Antibiotic LM 427; NSC 113926; Rifamycin S, dihydro-
EINECS	239-158-5

Quality Control

Our Rifamycin Sv is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes comprehensive analytical testing, including HPLC for assay and related substances, to meet exacting standards. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Orange-red to red-brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.