Description

4-o-[2-[(Butyl)Methylamino]-2-Oxoethyl]Rifamycin is a semi-synthetic derivative of the rifamycin class of antibiotics, specifically engineered for enhanced pharmacological properties. This compound is valued for its potent antibacterial activity, particularly against Gram-positive bacteria and mycobacteria, making it a critical intermediate in advanced pharmaceutical synthesis. It is primarily required by research institutions and pharmaceutical manufacturers developing next-generation anti-tuberculosis and anti-infective therapies.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of novel rifamycin-based antibiotics.
• Antibacterial Research: Used in microbiological and pharmacological research to study structure-activity relationships and mechanisms of action.
• API Development: Serves as a precursor in the development of Active Pharmaceutical Ingredients (APIs) targeting resistant bacterial strains.
• Veterinary Medicine: Potential application in developing antibacterial treatments for veterinary use.
• Reference Standard: Serves as a high-purity analytical reference standard for quality control and regulatory testing.

Basic Information

Product Name	4-o-[2-[(Butyl)Methylamino]-2-Oxoethyl]Rifamycin
CAS No.	16784-08-0
Molecular Formula	C39H52N2O13
Molecular Weight	756.84 g/mol
Synonyms	Rifamycin Derivative; 4-Deoxy-3,4-[2-[(N-butyl-N-methyl)glycyl]tetrahydro-1H,5H-pyrano[3,2-c][1]benzoxepin-5-ylidene]rifamycin SV; 4-Deoxy-3,4-[2-[(N-butyl-N-methyl)glycyl]tetrahydro-1H,5H-pyrano[3,2-c][1]benzoxepin-5-ylidene]rifamycin S; Butylmethylamino-oxoethyl Rifamycin; Rifamycin BMAOE
EINECS	Contact for details

Quality Control

Our 4-o-[2-[(Butyl)Methylamino]-2-Oxoethyl]Rifamycin is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to prevent oxidation and degradation. Keep the container in a dry, cool, and well-ventilated area.

Specification

Item	Specification
Appearance	Orange to red-brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.