Description

3-[(Methoxyimino)Methyl]Rifamycin is a key semi-synthetic derivative of the rifamycin class of antibiotics, primarily valued as a crucial intermediate in the synthesis of advanced antibacterial agents. Its significance lies in enabling the production of more potent and targeted rifamycin-based pharmaceuticals, which are essential in combating resistant bacterial strains. This high-purity intermediate is critically needed by pharmaceutical manufacturers and research institutions engaged in the development and production of next-generation anti-tuberculosis and anti-MRSA drugs.

Application

• Pharmaceutical Intermediate: Primary use as a critical building block in the synthesis of advanced rifamycin antibiotics like Rifaximin and Rifampicin derivatives.
• Antibacterial Drug Development: Serves as a core scaffold in R&D for novel antibiotics targeting drug-resistant bacteria, including Mycobacterium tuberculosis.
• Active Pharmaceutical Ingredient (API) Manufacturing: Used in the controlled production of final API batches under Good Manufacturing Practice (GMP) conditions.
• Biochemical Research: Employed in microbiological and pharmacological studies to understand structure-activity relationships within the rifamycin family.
• Veterinary Medicine Synthesis: Potential application in developing antibacterial treatments for veterinary use.

Basic Information

Product Name	3-[(Methoxyimino)Methyl]Rifamycin
CAS No.	13292-54-1
Molecular Formula	C38H47N3O12
Molecular Weight	737.80 g/mol
Synonyms	Rifamycin O-Methyloxime; 3-[(Methoxyimino)methyl]rifamycin SV; 3-Formylrifamycin SV O-methyloxime; Rifamycin, 3-[(methoxyimino)methyl]-; (3-Formylrifamycin SV) O-methyloxime; Rifamycin O-methyloxime derivative; Antibiotic X 149
EINECS	Contact for details

Quality Control

Our 3-[(Methoxyimino)Methyl]Rifamycin is manufactured and tested to meet stringent quality standards suitable for pharmaceutical intermediate applications. We provide comprehensive quality assurance with batch-specific Certificates of Analysis (COA) that detail purity, identity, and impurity profiles. Our quality systems are designed to support regulatory requirements for pharmaceutical development and manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	Orange-red to brownish-red powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.