Description

Rifamycin O is a key intermediate in the synthesis of clinically significant rifamycin antibiotics. This compound is valued for its role in producing potent antimicrobial agents used to combat serious bacterial infections. It is primarily required by pharmaceutical manufacturers and research institutions engaged in antibiotic development and production. Rifamycin O CAS NO 14487-05-9 is a critical building block for ensuring a reliable supply chain for essential medicines.

Application

• Pharmaceutical Intermediate: Primary use as a precursor in the synthesis of Rifamycin S and other rifamycin-class antibiotics.
• Antibiotic Production: A crucial raw material in the manufacturing process of broad-spectrum antibiotics for treating tuberculosis and other mycobacterial infections.
• Research & Development: Used in biochemical and microbiological research to study antibiotic mechanisms of action and resistance.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical labs.
• Chemical Synthesis: Employed in organic synthesis for the development of novel antimicrobial derivatives and analogs.

Basic Information

Product Name	Rifamycin O
CAS No.	14487-05-9
Molecular Formula	C37H47NO12
Molecular Weight	697.77 g/mol
Synonyms	Rifamycin O; Rifamycin-O; 25-Deacetylrifamycin S; Rifamycin O (8.5%); Antibiotic AF/ABD; AF/ABD Complex; Rifamycin O, 25-Deacetylrifamycin S; (12Z,14E,24E)-(2S,12S,13S,14R,15S,16R,17S,18R,19R,20S,21S,22R,23S)-5,6,9,17,19-Pentahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-2,7-(epoxypentadeca[1,11,13]trienimino)benzofuro[4,5-e]pyrido[1,2-a]benzimidazole-8-carboxylic acid
EINECS	Contact for details

Quality Control

Our Rifamycin O is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) are provided with every shipment, detailing all specified parameters. We adhere to cGMP principles where applicable to support our global customer base.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere such as nitrogen or argon to maintain stability and potency.

Specification

Item	Specification
Appearance	Yellow to orange-yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.