Description

3-((Dimethylhydrazono)Methyl)Rifamycin Sv is a chemically modified derivative of the potent ansamycin antibiotic Rifamycin S. This compound is a key intermediate in the synthesis of advanced rifamycin antibiotics, offering a crucial building block for pharmaceutical research and development. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the development of novel antibacterial agents targeting resistant bacterial strains.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of semi-synthetic rifamycin antibiotics, such as Rifampicin and Rifabutin.
• Antibacterial Research: Serves as a key scaffold in medicinal chemistry programs aimed at discovering new antibacterial compounds with improved efficacy against drug-resistant bacteria.
• Biochemical Studies: Used in research to study the structure-activity relationships (SAR) of ansamycin antibiotics and their interaction with bacterial RNA polymerase.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for the identification and quantification of related rifamycin compounds.

Basic Information

Product Name	3-((Dimethylhydrazono)Methyl)Rifamycin Sv
CAS No.	13292-34-7
Molecular Formula	C39H49N3O12
Molecular Weight	751.82 g/mol
Synonyms	3-[(Dimethylhydrazono)methyl]rifamycin SV; 3-Formylrifamycin SV dimethylhydrazone; Rifamycin SV 3-dimethylhydrazone; Rifamycin SV dimethylhydrazone; N,N-Dimethyl-N'-(3-formylrifamycin SV)hydrazone; (E)-3-((Dimethylhydrazono)methyl)rifamycin SV; Rifamycin Derivative 13292-34-7
EINECS	Contact for details

Quality Control

Our 3-((Dimethylhydrazono)Methyl)Rifamycin Sv is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C to -10°C under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation. Allow the container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	Reddish-brown to orange crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.