Description

Cholyltetraglycylhistamine CAS NO 98584-70-4 is a synthetic peptide derivative of cholic acid, conjugated with a tetraglycylhistamine moiety. This specialized compound is valued for its role as a high-affinity ligand and a key intermediate in advanced biochemical research and diagnostic development. It is primarily utilized by research institutions and pharmaceutical developers focused on hepatobiliary function, receptor studies, and the creation of novel assay systems.

Application

• As a critical research biochemical for studying bile acid receptors and transporters.
• As a high-affinity binding agent or conjugate in the development of immunoassays and diagnostic kits.
• As a specialized intermediate in the synthesis of targeted probes for molecular imaging.
• For in vitro studies investigating hepatobiliary pathways and cellular signaling.
• In the development of affinity chromatography media for protein purification.
• As a reference standard in analytical method development for pharmaceutical quality control.

Basic Information

Item	Detail
Product Name	Cholyltetraglycylhistamine
CAS No.	98584-70-4
Molecular Formula	C41H68N8O10
Molecular Weight	833.03 g/mol
Synonyms	Cholyl-Gly-Gly-Gly-Gly-His-NH2; Cholic Acid-(tetraglycylhistamine) Conjugate; N-[(3α,5β,7α,12α)-3,7,12-Trihydroxy-24-oxocholan-24-yl]tetraglycylhistamine; Taurocholyletraglycylhistamine (related analog); Bile Acid-Peptide Conjugate; Research Biochemical 98584-70-4; CG4H
EINECS	Contact for details

Quality Control

Our Cholyltetraglycylhistamine is produced under a rigorous quality management system. Each batch is characterized and tested to ensure identity, purity, and consistency suitable for research applications. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), identity confirmation (by MS and NMR), and other critical parameters is provided to guarantee reliable and reproducible performance in your experiments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.