Description

Cholyldiglycylhistamine is a specialized peptide derivative of significant interest in advanced biochemical research and development. This compound is valued for its role as a synthetic intermediate and a model substrate in enzymatic and receptor-binding studies. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications ranging from drug discovery to biochemical assay development.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel peptide-based therapeutics and diagnostic agents.
• Biochemical Research: Serves as a key substrate or ligand in enzymatic studies, particularly those involving cholylglycine hydrolase or related enzymes.
• Receptor Binding Assays: Employed in in vitro studies to investigate interactions with bile acid receptors or histamine receptors.
• Metabolic Pathway Analysis: Acts as a tool compound for studying bile acid conjugation and peptide metabolism pathways.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Cholyldiglycylhistamine
CAS No.	98584-68-0
Molecular Formula	C34H54N6O7
Molecular Weight	658.84 g/mol
Synonyms	N-[(3α,5β,7α,12α)-3,7,12-Trihydroxy-24-oxocholan-24-yl]glycylglycylhistamine; Cholyl-Gly-Gly-His-NH2; Glycylglycylhistamine cholate; Taurocholyldiglycylhistamine analog; Bile acid-peptide conjugate; Cholylglycylglycylhistamine
EINECS	Contact for details

Quality Control

Our Cholyldiglycylhistamine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.