Description

14(S),15(R)-Epoxy-(5Z,8Z,11Z)-Eicosatrienoic Acid is a specialized epoxy fatty acid derivative, serving as a key intermediate in the synthesis of bioactive lipid mediators. This compound matters for its role as a precursor in the biosynthesis of eicosanoids, which are critical signaling molecules involved in various physiological and pathological processes. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced chemical synthesis sectors for drug discovery, biochemical research, and the production of reference standards.

Application

• Biochemical Research: Used as a critical intermediate in studying the cytochrome P450 epoxygenase pathway and the metabolism of arachidonic acid.
• Pharmaceutical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in drug discovery and development.
• Eicosanoid Synthesis: A key precursor for the chemical or enzymatic synthesis of downstream epoxy-eicosatrienoic acids (EETs) and other related lipid mediators.
• Cell Signaling Studies: Employed in in vitro and in vivo models to investigate the role of epoxy fatty acids in cardiovascular, renal, and inflammatory processes.
• Enzyme Activity Assays: Utilized as a substrate to assay the activity of soluble epoxide hydrolase (sEH) and other metabolizing enzymes.

Basic Information

Product Name	14(S),15(R)-Epoxy-(5Z,8Z,11Z)-Eicosatrienoic Acid
CAS No.	98103-48-1
Molecular Formula	C₂₀H₃₂O₃
Molecular Weight	320.47 g/mol
Synonyms	14(S),15(R)-EET; 14,15-Epoxy-5Z,8Z,11Z-eicosatrienoic Acid; 14(S),15(R)-Epoxyeicosatrienoic Acid; 14,15-EET; (14S,15R)-Epoxy-(5Z,8Z,11Z)-eicosatrienoic Acid; 14,15-Epoxy-5,8,11-eicosatrienoic Acid; Arachidonic Acid 14,15-Epoxide
EINECS	Contact for details

Quality Control

Our 14(S),15(R)-Epoxy-(5Z,8Z,11Z)-Eicosatrienoic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere such as argon or nitrogen, as the compound is easily oxidized. Allow the container to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Enantiomeric Excess (Chiral HPLC)	≥ 98%
Solubility	Soluble in ethanol, DMSO, DMF; slightly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.