Description

15-Hydroxy-5,8,11,13,17-Eicosapentaenoic Acid (15-HEPE) is a specialized, bioactive metabolite of eicosapentaenoic acid (EPA), a key ω-3 fatty acid. This compound is valued for its role as a signaling molecule and intermediate in the biosynthesis of specialized pro-resolving mediators (SPMs), which are crucial for regulating inflammatory processes. It is primarily utilized by research institutions and pharmaceutical developers focused on inflammation resolution, metabolic studies, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a high-purity reference standard and intermediate in studies of lipid metabolism, inflammation pathways, and the biosynthesis of resolvins.
• Pharmaceutical R&D: Serves as a critical starting material or intermediate for the synthesis of novel anti-inflammatory and pro-resolving lipid mediators.
• Nutraceutical Development: Investigated for potential applications in advanced dietary supplements targeting metabolic and inflammatory health.
• Cell Culture & In Vitro Studies: Employed in cell-based assays to study receptor interactions, signaling cascades, and cellular responses to oxylipins.
• Analytical Standard: Essential for the calibration and validation of analytical methods (HPLC, LC-MS) in laboratories quantifying oxylipin profiles in biological samples.

Basic Information

Product Name	15-Hydroxy-5,8,11,13,17-Eicosapentaenoic Acid
CAS No.	97850-14-1
Molecular Formula	C₂₀H₃₀O₃
Molecular Weight	318.45 g/mol
Synonyms	15-HEPE; (5Z,8Z,11Z,13E,15S,17Z)-15-Hydroxyicosa-5,8,11,13,17-pentaenoic acid; 15(S)-HEPE; 15-Hydroxy-EPA; 15-HETE (5,8,11,13,17); 15-Hydroxyeicosapentaenoic acid
EINECS	Contact for details

Quality Control

Our 15-Hydroxy-5,8,11,13,17-Eicosapentaenoic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) with batch-specific data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Solubility	Soluble in ethanol, DMSO; slightly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.