Description

1-o-(cis-9-Octadecenyl)-Sn-Glycero-3-Phosphocholine is a synthetic, single-chain ether-linked phospholipid, a key structural analog of platelet-activating factor (PAF). This compound matters for its role as a crucial biochemical tool and a versatile building block in advanced lipid research and formulation. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced material science sectors for developing targeted drug delivery systems, creating biomimetic membranes, and studying cell signaling pathways.

Application

• Liposome & Nanoparticle Formulation: As a key component for creating stable, long-circulating liposomal drug carriers and lipid nanoparticles (LNPs) for mRNA and gene delivery.
• Biomembrane Research: Used to construct model membranes and lipid bilayers to study membrane fluidity, protein-lipid interactions, and cellular processes.
• Biochemical & Cell Signaling Studies: Serves as a reference standard and precursor in the investigation of platelet-activating factor (PAF) metabolism and related inflammatory pathways.
• Pharmaceutical Excipient: Employed as a functional excipient to enhance the solubility, stability, and bioavailability of poorly soluble active pharmaceutical ingredients (APIs).
• Diagnostic Reagent Development: Utilized in the synthesis of fluorescent or tagged lipid probes for cellular imaging and diagnostic assays.
• Cosmetic & Dermal Formulations: Incorporated into high-end cosmetic products for its biomimetic properties, aiding in skin barrier repair and active ingredient delivery.

Basic Information

Product Name	1-o-(cis-9-Octadecenyl)-Sn-Glycero-3-Phosphocholine
CAS No.	97802-55-6
Molecular Formula	C₂₆H₅₄NO₆P
Molecular Weight	499.69 g/mol
Synonyms	1-O-(cis-9-Octadecenyl)-2-O-acetyl-sn-glycero-3-phosphocholine (PAF precursor); 1-O-Octadec-9-enyl-sn-glycero-3-phosphocholine; 1-O-(9Z-Octadecenyl)-sn-glycero-3-phosphocholine; Lyso-PAF C-18:1; 1-O-(Oleyl)-sn-glycero-3-phosphocholine; Ether-linked Lysolectihin C-18:1; 1-O-(9Z-Octadecenyl)-2-hydroxy-sn-glycero-3-phosphocholine; sn-Glycero-3-phosphocholine 1-(9Z-octadecenyl) ether
EINECS	Contact for details

Quality Control

Our 1-o-(cis-9-Octadecenyl)-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and formulation. Certificates of Analysis (COA) with detailed chromatographic data are available upon request. We can support development projects requiring compliance with cGMP or other specific regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. For short-term use, store desiccated at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white waxy solid or film
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0% (Area %)
Assay (NMR)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.