Description

Lappaconitine Hydrobromide is a high-purity alkaloid salt derived from specific Aconitum species. This compound is valued for its potent biological activity, making it a critical reference standard and active pharmaceutical ingredient (API) in advanced research and development. It is primarily utilized by the pharmaceutical, biotechnology, and academic research sectors for pharmacological studies, analytical method development, and as a key intermediate in specialized syntheses.

Application

• Pharmaceutical Reference Standard: Serves as a certified standard for quality control, assay calibration, and method validation in drug development and manufacturing.
• Neurological & Pain Research: Used as a key investigational compound in preclinical studies targeting sodium channels, analgesia, and neuropharmacology.
• Active Pharmaceutical Ingredient (API): Employed as a principal component in the formulation of specialized pharmaceutical preparations.
• Biochemical Research: Utilized in studies of ion channel function, receptor binding assays, and other mechanistic biological investigations.
• Analytical Chemistry: Acts as a high-purity analyte for developing and testing analytical methods such as HPLC, LC-MS, and NMR.
• Academic & Institutional Research: Supplied to universities and research institutes for chemical, pharmacological, and toxicological studies.

Basic Information

Product Name	Lappaconitine Hydrobromide
CAS No.	97792-45-5
Molecular Formula	C32H44N2O8 • HBr
Molecular Weight	665.62 g/mol
Synonyms	Lappaconitine HBr; N-Deacetyllappaconitine hydrobromide; (1α,14α,16β)-20-Ethyl-1,14,16-trimethoxyaconitane-4,8,9-triol 4-benzoate 8-acetate 9-veratrate hydrobromide; Lappaconitinium bromide; Aconitum alkaloid hydrobromide salt
EINECS	Contact for details

Quality Control

Our Lappaconitine Hydrobromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets stringent specifications for research and pharmaceutical use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.