Description

1-Pyrenebutanoicacidsuccinimidylester CAS NO 97427-71-9 is a high-purity, functionalized pyrene derivative widely used as a versatile labeling and crosslinking reagent. This compound is critical for researchers and manufacturers requiring reliable, site-specific conjugation of biomolecules due to its reactive N-hydroxysuccinimide (NHS) ester group. It is primarily utilized in the development of advanced fluorescent probes, sensors, and materials within the life sciences, diagnostics, and specialty chemical sectors.

Application

• Fluorescent Labeling of Biomolecules: Conjugation to proteins, antibodies, peptides, and oligonucleotides for fluorescence microscopy, flow cytometry, and immunoassays.
• Development of Biosensors and Probes: Synthesis of sensitive fluorescent probes for detecting ions, small molecules, or enzymatic activity.
• Material Science and Polymer Chemistry: Incorporation into polymers, dendrimers, or nanoparticles to create functional materials with intrinsic fluorescence for tracking or sensing applications.
• Surface Modification and Immobilization: Functionalization of glass, silicon, or polymer surfaces with pyrene groups for creating biochips or sensor platforms.
• Energy Transfer Studies: Acting as a donor or acceptor in Förster Resonance Energy Transfer (FRET) systems for studying molecular interactions and distances.
• Pharmaceutical Research: Labeling of drug candidates or carriers for pharmacokinetic and biodistribution studies.

Basic Information

Product Name	1-Pyrenebutanoicacidsuccinimidylester
CAS No.	97427-71-9
Molecular Formula	C24H19NO4
Molecular Weight	385.41 g/mol
Synonyms	1-Pyrenebutyric Acid N-Hydroxysuccinimide Ester; 1-Pyrenebutanoic Acid Succinimidyl Ester; 1-PBASE; Pyrene-1-butyric Acid N-Succinimidyl Ester; 4-(1-Pyrenyl)butanoic Acid 2,5-Dioxo-1-pyrrolidinyl Ester; 1-Pyrenebutyric Acid NHS Ester; N-(1-Pyrenebutyryloxy)succinimide; 1-Pyrenebutanoic Acid, N-Succinimidyl Ester
EINECS	Contact for details

Quality Control

Our 1-Pyrenebutanoicacidsuccinimidylester is manufactured under strict quality protocols to ensure batch-to-batch consistency and high performance. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This compound is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. For long-term storage, keep under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMF, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.