Description

Phosphatidylcholine, L-α-Dipalmitoyl, [Dipalmitoyl-1-14C] is a high-purity, carbon-14 radiolabeled phospholipid essential for advanced research and development. This compound is critically important for precise metabolic and pharmacokinetic studies, enabling the detailed tracking of lipid pathways in biological systems. It is primarily required by pharmaceutical R&D laboratories, academic research institutions, and specialized contract research organizations (CROs) focused on drug delivery, membrane biology, and lipid metabolism.

Application

• Tracer Studies in Lipid Metabolism: Used as a radiolabeled tracer to investigate the absorption, distribution, metabolism, and excretion (ADME) of phospholipids in vivo and in vitro.
• Drug Delivery System Research: A key component in the development and characterization of liposomal and nanoparticle-based drug delivery vehicles, allowing for precise quantification of carrier fate.
• Membrane Biophysics & Biochemistry: Employed in studies of membrane fluidity, fusion, and the assembly of lipid bilayers to understand fundamental cellular processes.
• Biomedical Imaging & Diagnostics: Serves as a precursor for developing labeled probes for imaging techniques, aiding in the visualization of biological targets.
• Pharmaceutical Formulation Development: Used to optimize and validate the stability and efficacy of lipid-based formulations in pre-clinical stages.
• Metabolic Pathway Analysis: Facilitates the elucidation of specific enzymatic pathways involved in phospholipid synthesis and degradation.

Basic Information

Product Name	Phosphatidylcholine, L-α-Dipalmitoyl, [Dipalmitoyl-1-14C]
CAS No.	97423-96-6
Molecular Formula	C40H78NO8P * (14C-labeled)
Molecular Weight	~734.0 g/mol (unlabeled)
Synonyms	1,2-Dipalmitoyl-sn-glycero-3-phosphocholine (14C-labeled); DPPC-14C; L-α-Dipalmitoylphosphatidylcholine-14C; 1,2-Dihexadecanoyl-sn-glycero-3-phosphocholine (14C-labeled); [1-14C]DPPC; Radiolabeled DPPC; Phosphatidylcholine, 1,2-dipalmitoyl-(carbonyl-14C); Cardiolipin precursor (labeled)
EINECS	Contact for details

Quality Control

Every batch of our radiolabeled Phosphatidylcholine, L-α-Dipalmitoyl, [Dipalmitoyl-1-14C] is manufactured and handled under strict quality systems to ensure high chemical and radiochemical purity, specific activity, and stability. Comprehensive analytical testing, including HPLC, TLC, and radiometric detection, is performed. A detailed Certificate of Analysis (COA) specifying purity, specific activity (mCi/mmol or GBq/mmol), and solvent composition is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at or below -20°C under an inert atmosphere (argon or nitrogen). This product is strictly light-sensitive (protect from all light exposure) and easily oxidized (store under inert atmosphere). Always handle in accordance with radiation safety protocols for carbon-14.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (HPLC, TLC)	Conforms to reference standard
Chemical Purity (HPLC)	≥ 98%
Radiochemical Purity	≥ 97%
Specific Activity	50-60 mCi/mmol (1.85-2.22 GBq/mmol) [Custom ranges available]
Solvent (if supplied in solution)	Specified Chloroform, Ethanol, or custom solvent blend
Concentration	As per customer request (e.g., 1.0 mCi/mL)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.