Description

Poly(2-Amino-8-Methyladenylic Acid) is a synthetic polynucleotide analog derived from a modified adenine base. This specialized compound is valued for its unique structural properties, which make it a critical tool in advanced biochemical and pharmaceutical research. It is primarily utilized by research institutions and biotechnology companies focused on nucleic acid chemistry, drug discovery, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a model compound or substrate in enzymatic studies involving polymerases and nucleases.
• Pharmaceutical Development: Serves as a building block or intermediate in the synthesis of oligonucleotide-based therapeutics and prodrugs.
• Molecular Biology: Employed in studies investigating nucleic acid structure, stability, and hybridization properties of modified polynucleotides.
• Antiviral/Anticancer Research: Investigated for potential biological activity due to its modified nucleobase structure, which can interfere with viral replication or cellular processes.
• Diagnostic Probe Development: Potential use in creating specialized probes for detecting specific DNA or RNA sequences.

Basic Information

Product Name	Poly(2-Amino-8-Methyladenylic Acid)
CAS No.	97374-44-2
Molecular Formula	(C11H14N5O7P)n
Molecular Weight	Contact for details
Synonyms	Poly(2-amino-8-methyladenosine 5'-phosphate); Poly(2-amino-8-methyladenylic acid) sodium salt; 2-Amino-8-methyladenosine polynucleotide; Poly(2-NH2-8-MeA); 8-Methyl-2-aminoadenylic acid polymer; Poly(8-methylisoguanosine 5'-phosphate) (related analog); PMeA polymer
EINECS	Contact for details

Quality Control

Our Poly(2-Amino-8-Methyladenylic Acid) is produced under controlled conditions to ensure batch-to-batch consistency and high purity. Quality is verified through a suite of analytical techniques including HPLC, UV-Vis spectroscopy, and gel electrophoresis to confirm polymer length distribution and chemical identity. Certificates of Analysis (COA) detailing purity, assay, and other critical parameters are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive) and must be handled in a dry environment. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid or lyophilized powder
Identification (UV/VIS)	Characteristic absorption spectrum
Identification (HPLC)	Corresponds to reference standard
Assay (HPLC)	≥ 90% (Polymer content)
Moisture Content (KF)	≤ 5.0 %
Average Chain Length (n)	Contact for details
Endotoxin (LAL)	< 10 EU/mg (if required)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.