Description

Benzo(A)Pyrene-3,6-Quinol Diglucuronide is a crucial glucuronide conjugate metabolite of benzo[a]pyrene, a well-studied polycyclic aromatic hydrocarbon (PAH). This compound serves as a vital analytical standard and reference material for environmental monitoring, toxicology research, and metabolic pathway studies. It is primarily needed by analytical laboratories, contract research organizations (CROs), and academic institutions focused on carcinogen metabolism, biomarker analysis, and regulatory compliance testing.

Application

• Analytical Reference Standard: Used as a high-purity calibrant in HPLC, LC-MS, and GC-MS for the quantification of PAH metabolites in biological and environmental samples.
• Toxicology & Metabolic Studies: Essential for researching the metabolic fate, detoxification pathways, and excretion profiles of benzo[a]pyrene in vivo.
• Biomarker Development: Serves as a key compound in developing and validating assays for PAH exposure biomarkers in urine or serum for occupational health monitoring.
• Environmental Science: Applied in studies assessing human exposure to combustion products and environmental pollutants.
• Pharmaceutical Research: Used in investigations of drug-metabolizing enzyme activities, specifically UDP-glucuronosyltransferases (UGTs).
• Quality Control: Employed as an internal standard in analytical laboratories to ensure accuracy and precision in PAH metabolite testing.

Basic Information

Product Name	Benzo(A)Pyrene-3,6-Quinol Diglucuronide
CAS No.	97287-75-7
Molecular Formula	C32H34O14
Molecular Weight	642.61 g/mol
Synonyms	3,6-Dihydroxybenzo[a]pyrene diglucuronide; BP-3,6-quinol diglucuronide; Benzo[a]pyrene-3,6-diol, 3,6-bis(β-D-glucopyranosiduronic acid); 3,6-Bis(β-D-glucopyranosiduronic acid)benzo[a]pyrene-3,6-diol; Benzo[a]pyrene-3,6-quinol bis(β-D-glucuronide); B[a]P-3,6-quinol diglucuronide; PAH metabolite standard
EINECS	Contact for details

Quality Control

Our Benzo(A)Pyrene-3,6-Quinol Diglucuronide is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and analysis. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. Keep the container in a dry, cool, and well-ventilated place. For long-term storage, consider storing desiccated at -20°C.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, Methanol; Slightly soluble in Water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.