Description

1,3,5[10]-Estratriene-3,16Alpha,17Beta-Triol 16-Glucuronide Sodium Salt is a high-purity conjugated metabolite of estriol, a naturally occurring estrogen. This compound is of significant value as a critical reference standard and analytical reagent for precise quantification in clinical and research settings. It is primarily required by pharmaceutical R&D laboratories, diagnostic kit manufacturers, and academic research institutions focusing on endocrinology and steroid metabolism.

Application

• Primary Reference Standard for the calibration and validation of analytical methods (HPLC, LC-MS/MS) in bioanalytical laboratories.
• Critical Component in the development and quality control of in-vitro diagnostic (IVD) kits for hormone level testing.
• Metabolite Standard for pharmacokinetic and drug metabolism studies related to estrogen-based therapeutics.
• Research Reagent in biochemical studies investigating estrogen conjugation, transport, and excretion pathways.
• Calibrator Material for ensuring accuracy and traceability in clinical chemistry assays measuring estriol glucuronides.

Basic Information

Product Name	1,3,5[10]-Estratriene-3,16Alpha,17Beta-Triol 16-Glucuronide Sodium Salt
CAS No.	1852-44-4
Molecular Formula	C24H31NaO9
Molecular Weight	486.49 g/mol
Synonyms	Estriol 16-Glucuronide Sodium Salt; Estratriene-3,16α,17β-triol 16-(β-D-glucopyranosiduronic acid) sodium salt; 16α-Hydroxyestriol 16-Glucuronide Sodium Salt; Sodium Estriol 16-Glucuronide; Estriol 16α-Glucuronide Sodium; NSC 49195; 16-Glucuronide of Estriol Sodium Salt
EINECS	Contact for details

Quality Control

Our 1,3,5[10]-Estratriene-3,16Alpha,17Beta-Triol 16-Glucuronide Sodium Salt is manufactured under strict quality systems to ensure batch-to-batch consistency and reliability as an analytical standard. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, generated using validated methods such as HPLC and NMR. We support compliance with GMP and ISO 17025 principles for reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	Conforms
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.