Description

Rac Cotinine CAS NO 15569-85-4 is a high-purity analytical reference standard and a key intermediate in pharmaceutical research. This compound is essential for the calibration and validation of analytical methods, ensuring accurate measurement and quality control in critical applications. It is primarily utilized by research institutions, diagnostic laboratories, and pharmaceutical companies engaged in nicotine metabolism studies, biomarker analysis, and the development of smoking cessation aids.

Application

• Analytical Reference Standard: Used for the calibration of HPLC, LC-MS, and GC-MS systems in quantitative bioanalysis.
• Biomarker Research: Serves as a primary metabolite and biomarker for nicotine exposure in clinical and forensic toxicology studies.
• Pharmaceutical Intermediate: Employed in the synthesis and development of novel therapeutics and diagnostic agents related to nicotine dependence.
• Diagnostic Kit Manufacturing: A critical component in the production of immunoassay kits for cotinine detection in bodily fluids.
• Metabolic Pathway Studies: Facilitates research into the pharmacokinetics and pharmacodynamics of nicotine and related alkaloids.
• Quality Control (QC) Testing: Acts as a system suitability standard in pharmaceutical QC laboratories to ensure method accuracy.

Basic Information

Item	Details
Product Name	Rac Cotinine
CAS No.	15569-85-4
Molecular Formula	C10H12N2O
Molecular Weight	176.22 g/mol
Synonyms	(±)-Cotinine; DL-Cotinine; rac-Cotinine; 1-Methyl-5-(3-pyridyl)-2-pyrrolidinone; NSC 143491; Cotinine Racemate; Nicotine Metabolite N-Oxide (reduced); 2-Pyrrolidinone, 1-methyl-5-(3-pyridinyl)-
EINECS	Contact for details

Quality Control

Our Rac Cotinine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by IR and NMR, purity determination by HPLC, and residual solvent analysis by GC, to ensure it meets the stringent requirements for research and diagnostic use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.