Description

L-Tyrosine, 3,5-Di(Iodo-131I) is a radiolabeled derivative of the essential amino acid L-Tyrosine, where iodine-131 isotopes are specifically incorporated at the 3 and 5 positions of the aromatic ring. This compound is of critical importance for research and development in nuclear medicine, particularly in the synthesis of radiopharmaceuticals for diagnostic imaging and targeted radiotherapy. It is primarily utilized by pharmaceutical R&D laboratories, radiochemistry facilities, and academic institutions focused on oncology, neurology, and metabolic disorder research.

Application

• Radiopharmaceutical Precursor: Key intermediate in the synthesis of iodine-131 labeled compounds for targeted cancer therapy and diagnostic imaging.
• Metabolic Tracer Studies: Used in research to trace tyrosine metabolism and protein synthesis pathways in biological systems.
• Thyroid Research: Serves as a model compound for studying iodine uptake and organification mechanisms in thyroid physiology and related disorders.
• Drug Development: Employed in the development and evaluation of new therapeutic agents that target tyrosine-kinase pathways or require radiolabeling for pharmacokinetic studies.
• Molecular Imaging Probe Synthesis: Building block for creating specific probes used in Single Photon Emission Computed Tomography (SPECT).
• Biochemical Research: Tool for investigating enzyme activity, receptor binding, and other biochemical processes involving tyrosine residues.

Basic Information

Product Name	L-Tyrosine, 3,5-Di(Iodo-131I)
CAS No.	14679-68-6
Molecular Formula	C9H9131I2NO3
Molecular Weight	Contact for details
Synonyms	3,5-Diiodo-L-tyrosine-131I; L-3,5-Diiodotyrosine-131I; 3,5-Diiodo-131I-L-tyrosine; Radioiodinated L-DIT; [131I]DIT; (2S)-2-Amino-3-(4-hydroxy-3,5-di(131I)iodophenyl)propanoic acid; 131I-DIT
EINECS	Contact for details

Quality Control

Every batch of L-Tyrosine, 3,5-Di(Iodo-131I) is manufactured and controlled under a strict quality management system. Product specifications, including radiochemical purity, specific activity, and chemical purity, are verified using advanced analytical techniques such as HPLC and radio-TLC. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to ensure traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at the temperature specified on the label or accompanying documentation, typically in a shielded environment appropriate for radioactive materials (e.g., 2-8°C or as required). Handle and store in accordance with all applicable radiation safety regulations and guidelines.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/Radio-TLC)	Conforms
Assay (Radiochemical Purity)	≥ 95%
Specific Activity	Contact for details
Chemical Purity (HPLC)	≥ 98%
Radionuclidic Purity	≥ 99%
Solubility	Soluble in suitable solvents (e.g., aqueous base, DMSO)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.