Description

5-Hydroxyindole-3-Acetic Acid is a key indole derivative and a major metabolite of the neurotransmitter serotonin. This compound matters as a critical biochemical standard and research chemical for studying serotonergic pathways and related disorders. It is primarily needed by pharmaceutical R&D laboratories, diagnostic kit manufacturers, and academic institutions conducting neurochemical and metabolic research.

Application

• Biochemical Research Standard: Used as a primary reference standard in the quantification and study of serotonin metabolism.
• Diagnostic Reagent Manufacturing: A key component in the production of immunoassay kits for measuring 5-HIAA levels in biological fluids, aiding in the diagnosis of carcinoid tumors.
• Neuropharmacology Studies: Employed in research to investigate the pharmacology of serotonin and the mechanisms of action of psychotropic drugs.
• Metabolic Pathway Analysis: Utilized in vitro and in vivo studies to trace and understand indoleamine metabolic pathways.
• Academic & Institutional Research: Serves as a fundamental reagent for universities and research institutes focusing on neuroscience, endocrinology, and biochemistry.

Basic Information

Item	Detail
Product Name	5-Hydroxyindole-3-Acetic Acid
CAS No.	1321-73-9
Molecular Formula	C10H9NO3
Molecular Weight	191.18 g/mol
Synonyms	5-HIAA; 5-Hydroxy-3-indolylacetic acid; 5-Hydroxyindoleacetic acid; 3-(5-Hydroxy-1H-indol-3-yl)acetic acid; 5-Hydroxyindol-3-ylacetic acid; Serotonin metabolite; 5-Hydroxyindole acetate
EINECS	215-324-5

Quality Control

Our 5-Hydroxyindole-3-Acetic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the stringent requirements for research and diagnostic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.