Description

Cyanocobalamin Co 57 is a radioactive-labeled form of Vitamin B12, a critical cobalamin essential for numerous biological functions. This specific isotope, CAS NO 13115-03-2, is indispensable for research and diagnostic applications requiring precise tracking and quantification. It is primarily utilized by pharmaceutical R&D laboratories, clinical diagnostics manufacturers, and academic research institutions involved in metabolic studies, radioimmunoassays, and tracer methodology development.

Application

• Radioimmunoassay (RIA) Kits: Used as a labeled tracer for the quantitative measurement of Vitamin B12 and intrinsic factor in clinical serum samples.
• Metabolic Pathway Research: Serves as a radioactive tracer to study the absorption, distribution, metabolism, and excretion (ADME) of cobalamins in biological systems.
• Diagnostic Pharmaceutical Development: A key component in the development and calibration of in-vitro diagnostic (IVD) devices for pernicious anemia and B12 deficiency.
• Schilling Test Analog: Employed in research variants of the Schilling test to investigate Vitamin B12 absorption and gastrointestinal function.
• Biochemical Tracer Studies: Facilitates the study of binding kinetics to proteins like transcobalamin and haptocorrin in research settings.
• Quality Control Reference Standard: Acts as a reference material for calibrating equipment and validating methods in laboratories handling cobalamin analyses.

Basic Information

Product Name	Cyanocobalamin Co 57
CAS No.	13115-03-2
Molecular Formula	C₆₃H₈₈CoN₁₄O₁₄P *
Molecular Weight	1355.37 g/mol (unlabeled form)*
Synonyms	Vitamin B12 Co-57; Co-57 Labeled Cyanocobalamin; Cobalamin-57Co; Cyanocobalamin (57Co); Radioactive Vitamin B12; 57Co-Cyanocobalamin; Co57-Cyanocobalamin; α-(5,6-Dimethylbenzimidazolyl)cyanocobamide Co-57
EINECS	Contact for details

* Formula and weight are for the unlabeled compound. Specific activity and radioactive concentration are batch-specific.

Quality Control

Our Cyanocobalamin Co 57 is produced and handled under strict quality systems. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing critical parameters such as radioactive concentration, specific activity, radiochemical purity, and analytical purity. We ensure compliance with relevant guidelines for the handling and supply of radioactive materials for research use.

Storage

Preserve in a tightly closed container, protected from light. Store in appropriate shielded containment as per local radiation safety regulations at a controlled room temperature (15-25°C). The product is strictly light-sensitive (protect from all light exposure).

Specification

Item	Specification
Appearance	Dark red solution
Identification (Radio-TLC/HPLC)	Complies
Radiochemical Purity	≥ 95%
Specific Activity	Batch-specific (typically µCi/µg or MBq/µg range)
Radioactive Concentration	Batch-specific (typically µCi/mL or MBq/mL)
pH	4.0 - 7.0
Solvent	Aqueous ethanol or specified buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.