Description

Ruthenium Red is a distinctive inorganic coordination compound, widely recognized as a selective inhibitor of mitochondrial calcium uptake. This property makes it a critical research tool for studying cellular calcium signaling pathways and mitochondrial function. It is essential for researchers and manufacturers in life sciences, particularly for investigating mechanisms in cardiology, neurology, and cell biology. The compound is supplied as a high-purity material suitable for diagnostic and research applications.

Application

• Biomedical Research: Used as a potent and selective inhibitor of the mitochondrial calcium uniporter (MCU) to study calcium homeostasis, cell death (apoptosis/necrosis), and bioenergetics.
• Histology & Microscopy: Employed as a staining agent for pectin and mucopolysaccharides in plant and animal tissue samples for light and electron microscopy.
• Cardiovascular Studies: Applied in experimental models to investigate ischemia-reperfusion injury, myocardial protection, and calcium overload in cardiac cells.
• Neurobiological Research: Utilized to examine the role of mitochondrial calcium in neuronal excitotoxicity, neurodegenerative diseases, and synaptic transmission.
• Cell Biology Assays: Serves as a key reagent in assays designed to probe intracellular calcium flux and the relationship between mitochondrial function and cellular health.
• Diagnostic Reagent Manufacturing: Incorporated into the formulation of specialized kits and reagents for research and diagnostic purposes.

Basic Information

Product Name	Ruthenium Red
CAS No.	11103-72-3
Molecular Formula	Ru3O2(NH3)14Cl6 • nH2O
Molecular Weight	786.35 (Anhydrous)
Synonyms	Ammoniated Ruthenium Oxychloride; Ruthenium Red Chloride; Ruthenium Oxychloride Ammoniated; C.I. 77800; Ruthenium, [[(diammine)chlororuthenio]chloroaquaruthenio]di-μ-oxohexaamminedi-, chloride, hydrate; [Ru3O2(NH3)14]Cl6; RR
EINECS	234-349-0

Quality Control

Our Ruthenium Red is manufactured under strict quality protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling. A Certificate of Analysis (COA) detailing specific results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Brownish-red to dark brown powder
Identification (IR)	Conforms to structure
Assay (Ruthenium basis)	≥ 31.0 %
Purity (HPLC)	≥ 95.0 %
Solubility (in Water)	Clear, red solution
Loss on Drying	≤ 12.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.