Description

L-α-Phosphatidylinositol is a high-purity phospholipid, a crucial component of cell membranes and a vital signaling molecule. Its primary commercial value lies in its role as a precursor for the synthesis of phosphatidylinositol phosphates, which are central to numerous cellular processes. This makes it an essential raw material for research institutions, diagnostic kit manufacturers, and pharmaceutical companies developing lipid-based therapeutics and drug delivery systems.

Application

• Biomedical Research: Critical substrate for studying intracellular signaling pathways, enzyme kinetics (e.g., kinases, phospholipases), and membrane biology.
• Pharmaceutical Development: Used in the formulation of liposomes and lipid nanoparticles (LNPs) for drug and gene delivery applications.
• Diagnostic Reagents: Serves as a key component in assay kits for measuring enzyme activities related to phosphoinositide metabolism.
• Cell Culture & Media Supplements: Employed as a lipid supplement in serum-free media to support the growth of specific cell lines.
• Biochemical Standard: Acts as a pure reference standard for analytical methods like HPLC and mass spectrometry in lipidomics.
• Cosmeceuticals: Incorporated into advanced skincare formulations for its potential membrane-stabilizing and barrier repair properties.

Basic Information

Product Name	L-α-Phosphatidylinositol
CAS No.	97281-52-2
Molecular Formula	C47H83O13P (typical for 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphoinositol)
Molecular Weight	~886.1 g/mol (varies with fatty acid composition)
Synonyms	Phosphatidylinositol; PI; 1,2-Diacyl-sn-glycero-3-phospho-(1D-myo-inositol); PtdIns; L-α-Phosphatidylinositol; myo-Inositol, 1,2-diacyl-sn-glycero-3-phospho-; Soy Phosphatidylinositol (source-specific)
EINECS	Contact for details

Quality Control

Our L-α-Phosphatidylinositol is produced and tested under strict quality management systems. Each batch is analyzed to ensure high purity and consistency, with specifications typically covering identification, assay, and impurity profiles. Certificates of Analysis (COA) detailing results from HPLC, TLC, and NMR are provided with every shipment. We can supply material suitable for research and GMP-grade applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. For long-term storage, desiccate. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white waxy solid or lyophilized powder
Identification (TLC/HPLC)	Conforms to standard
Assay (HPLC)	≥ 98.0% (Total Phosphatidylinositol)
Solubility	Soluble in chloroform, slightly soluble in ethanol, insoluble in water
Fatty Acid Composition	Specified by source (e.g., Soy, Bovine Liver) upon request
Loss on Drying	≤ 2.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.