Description

n-(10-(1-Pyrene)Decanoyl) Sphingomyelin is a specialized, fluorescently labeled derivative of sphingomyelin, a key phospholipid component of cell membranes. This compound is engineered for advanced research applications where precise tracking and visualization of lipid dynamics are required. It is an essential tool for researchers in biochemistry, cell biology, and biophysics studying membrane organization, lipid trafficking, and sphingolipid metabolism.

Application

• Fluorescent Labeling of Membranes: Acts as a vital probe for real-time visualization of sphingomyelin distribution and dynamics in artificial and cellular membranes using fluorescence microscopy.
• Lipid Raft and Microdomain Studies: Used to investigate the formation, stability, and function of lipid rafts and other membrane microdomains due to its preferential partitioning.
• Membrane Trafficking & Cellular Uptake: Tracks the intracellular transport, sorting, and metabolic fate of sphingolipids in live cells.
• Model Membrane Systems: Incorporated into liposomes, supported lipid bilayers, and other model systems to study lipid-protein interactions and membrane physical properties.
• Sphingolipid Metabolism Research: Serves as a substrate or tracer in enzymatic assays to study the activity of sphingomyelinases, synthases, and other metabolic enzymes.
• Drug Delivery & Targeting Research: Utilized in the development and characterization of lipid-based nanoparticle drug carriers to understand their interaction with biological membranes.

Basic Information

Product Name	n-(10-(1-Pyrene)Decanoyl) Sphingomyelin
CAS No.	97142-24-0
Molecular Formula	C53H85N2O6P
Molecular Weight	877.22 g/mol
Synonyms	Pyrene-Deca-Sphingomyelin; 1-O-[10-(1-Pyrenyl)decanoyl]-2-N-hexadecanoylsphingosylphosphorylcholine; N-(10-(1-Pyrene)decanoyl)sphingosylphosphorylcholine; Pyrene-labeled Sphingomyelin; Fluorescent Sphingomyelin; Pyrene-C10-SM; SM(Pyr); Pyrene Decanoyl Sphingomyelin
EINECS	Contact for details

Quality Control

Our n-(10-(1-Pyrene)Decanoyl) Sphingomyelin is produced under stringent conditions to ensure the highest standards of purity and batch-to-batch consistency, critical for sensitive research applications. Each batch is characterized by a comprehensive suite of analytical techniques including HPLC, MS, and NMR to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, keep under an inert atmosphere. Allow the sealed vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange solid or film
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Solubility	Soluble in chloroform, methanol, DMSO
Fluorescence Properties	Excitation ~340 nm, Emission ~376 nm (monomer)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.