Description

Nbd-Nystatin CAS NO 96475-98-8 is a fluorescently labeled derivative of the polyene macrolide antifungal agent, Nystatin. This modified compound is specifically designed for advanced research applications, offering a powerful tool for visualizing and studying the mechanism of action of antifungals. It is essential for scientists and researchers in pharmaceutical development and life sciences who require precise tracking of drug interactions. The product enables detailed investigation into cellular uptake and localization.

Application

• Mechanistic Antifungal Research: Used as a fluorescent probe to study the binding and action of polyene antibiotics on fungal cell membranes.
• Cellular Imaging and Localization: Enables visualization of drug uptake and distribution within fungal or mammalian cells using fluorescence microscopy.
• Biochemical Assay Development: Serves as a key reagent in developing high-throughput screening assays for novel antifungal compounds.
• Pharmacokinetic Studies: Aids in tracking the absorption and transport of nystatin analogs in experimental models.
• Diagnostic Probe Development: Potential use in creating diagnostic tools for detecting specific fungal pathogens.

Basic Information

Product Name	Nbd-Nystatin
CAS No.	96475-98-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	NBD-Nystatin; 7-Nitrobenz-2-oxa-1,3-diazol-4-yl-Nystatin; Nystatin-NBD; Fluorescent Nystatin Conjugate; Nystatin labeled with NBD; Nystatin-NBD conjugate; 4-(7-Nitro-2,1,3-benzoxadiazol-4-yl)nystatin
EINECS	Contact for details

Quality Control

Our Nbd-Nystatin is produced for research use under strict quality protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and performance consistency. Certificates of Analysis (COA) detailing purity (by HPLC), fluorescence properties, and other critical parameters are available upon request to support your research integrity.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccated conditions. Allow the product to equilibrate to room temperature before opening to minimize moisture condensation. For long-term stability, store in aliquots to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Yellow to orange solid or powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Fluorescence Properties	Ex/Em ~465/535 nm (solvent dependent)
Solubility	Soluble in DMSO, DMF; sparingly soluble in alcohols

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.