Description

S-(4-Nitrocarbobenzoxy)Glutathione is a specialized, chemically modified derivative of the essential tripeptide glutathione, designed for advanced biochemical research and synthesis. This compound serves as a critical intermediate and protecting group reagent, enabling precise studies of enzyme mechanisms, protein interactions, and redox biology. It is primarily utilized by researchers and manufacturers in the fields of pharmaceutical development, proteomics, and analytical chemistry for creating novel probes and investigating biochemical pathways.

Application

• Biochemical Research: Used as a key intermediate in the synthesis of enzyme inhibitors and activity-based probes for studying glutathione S-transferases and related enzymes.
• Proteomics & Protein Labeling: Serves as a protected glutathione derivative for site-specific protein conjugation and labeling studies.
• Pharmaceutical Intermediate: Acts as a building block in the research and development of novel therapeutic agents targeting oxidative stress and detoxification pathways.
• Analytical Standard: Employed as a high-purity reference standard in HPLC, LC-MS, and other chromatographic methods for quantitative analysis.
• Redox Biology Studies: Utilized in controlled experiments to investigate cellular redox signaling and the role of glutathionylation in protein function.

Basic Information

Product Name	S-(4-Nitrocarbobenzoxy)Glutathione
CAS No.	95998-72-4
Molecular Formula	C20H27N5O10S
Molecular Weight	529.52 g/mol
Synonyms	S-(4-Nitrobenzyloxycarbonyl)glutathione; Glutathione S-(4-nitrobenzyl) carbonate; NSC 401005; 4-Nitrobenzyl glutathione thioester; γ-Glu-Cys(S-4-nitrobenzyloxycarbonyl)-Gly; S-(p-Nitrobenzyloxycarbonyl)glutathione; S-(4-Nitrobenzyl) glutathione carbonate; N-(N-γ-L-Glutamyl-L-cysteinyl)glycine S-(4-nitrobenzyl) ester
EINECS	Contact for details

Quality Control

Our S-(4-Nitrocarbobenzoxy)Glutathione is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency suitable for research applications. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment and identity confirmation via spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.