Description

1-Palmitoyl-2-Pyrenedecanoylphosphatidylcholine is a synthetic, fluorescently labeled phospholipid, specifically designed for advanced membrane biophysics and cell biology research. Its core value lies in the incorporation of a pyrene fluorophore into the *sn-2* acyl chain, enabling sensitive detection and analysis of lipid dynamics, membrane fusion, and protein-lipid interactions. This high-purity, specialty lipid is essential for researchers and formulators in academic research, pharmaceutical development, and diagnostic assay manufacturing who require precise, reliable tools for probing complex biological systems.

Application

• Membrane Biophysics Research: As a fluorescent probe for studying lipid bilayer properties, phase transitions, and lateral diffusion using techniques like fluorescence spectroscopy and microscopy.
• Liposome & Nanoparticle Characterization: Used to label and track the stability, fusion, and cellular uptake of drug delivery vehicles such as liposomes and lipid nanoparticles (LNPs).
• Cell Biology Assays: Employed in fluorescence resonance energy transfer (FRET) assays to monitor membrane proximity, fusion events, and protein binding in real-time.
• Model Membrane Systems: A key component in creating artificial membranes (e.g., supported lipid bilayers, giant unilamellar vesicles) for controlled experimental studies.
• Enzymology Studies: Serves as a specific substrate for investigating the activity and kinetics of phospholipases and other lipid-modifying enzymes.
• Diagnostic Development: Can be utilized in the development of fluorescent-based diagnostic kits and sensors that target membrane-associated processes.

Basic Information

Product Name	1-Palmitoyl-2-Pyrenedecanoylphosphatidylcholine
CAS No.	95864-17-8
Molecular Formula	C55H86NO8P
Molecular Weight	920.25 g/mol
Synonyms	16:0-12:0 Pyrene PC; 1-Hexadecanoyl-2-(1-pyrenedecanoyl)-sn-glycero-3-phosphocholine; Pyrene-labeled Phosphatidylcholine; Pyrene-PC; 1-Palmitoyl-2-(1-pyrenedecanoyl)-sn-glycero-3-phosphocholine; Fluorescent Phosphatidylcholine; Ppyrene Phospholipid; N-((6-(1-Pyrenyl)decanoyl)-1-palmitoyl-2-lyso-sn-glycero-3-phospho)choline
EINECS	Contact for details

Quality Control

Our 1-Palmitoyl-2-Pyrenedecanoylphosphatidylcholine is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as purity (by HPLC), identity confirmation, and impurity profiles. We adhere to cGMP principles for production and control, ensuring traceability and reliability for our global B2B clients in the life sciences sector.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to ensure long-term stability. This product is hygroscopic (moisture-sensitive) and strictly light-sensitive; therefore, it should be handled in a controlled environment and allowed to equilibrate to room temperature in a desiccator before opening to prevent condensation and degradation.

Specification

Item	Specification
Appearance	Yellow to orange solid or film
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Pyrene Content (Fluorimetry)	Conforms to theoretical value
Solubility	Soluble in chloroform, methanol; forms clear solutions
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.