Description

14α-Hydroxy Prednisolone is a synthetic corticosteroid derivative and a key intermediate in the synthesis of more complex steroid-based pharmaceuticals. This compound is valued for its role in developing novel anti-inflammatory and immunosuppressive agents with potentially enhanced therapeutic profiles. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in steroid chemistry and advanced drug development.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel corticosteroid drugs and prodrugs.
• Research & Development: Used in biochemical and pharmacological research to study steroid metabolism, receptor binding, and structure-activity relationships (SAR).
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Chemical Synthesis: Employed in organic synthesis to introduce the 14α-hydroxy functionality into steroid backbones for further chemical modifications.

Basic Information

Product Name	14α-Hydroxy Prednisolone
CAS No.	95815-58-0
Molecular Formula	C21H28O6
Molecular Weight	376.45 g/mol
Synonyms	14α-Hydroxyprednisolone; 11β,14α,17α,21-Tetrahydroxypregna-1,4-diene-3,20-dione; 14α-Hydroxy-11β,17α,21-trihydroxypregna-1,4-diene-3,20-dione; Prednisolone, 14α-hydroxy-; 14α-OH Prednisolone
EINECS	Contact for details

Quality Control

Our 14α-Hydroxy Prednisolone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical intermediates and research chemicals. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.