Description

2'-O-(N-(2-Aminoethyl)Carbamoylethyl)Phosphono-Nad is a chemically modified NAD (Nicotinamide Adenine Dinucleotide) analog, specifically engineered with a reactive aminoethyl carbamoylethyl phosphonate moiety. This modification is critical for creating stable, site-specific conjugates, making it a valuable tool in advanced biochemical research and diagnostic development. It is primarily utilized by researchers and manufacturers in the fields of enzymology, molecular biology, and the development of novel biosensors and therapeutic agents.

Application

• Enzyme Activity Studies: Used as a substrate or inhibitor analog to investigate NAD-dependent enzyme mechanisms, including dehydrogenases and sirtuins.
• Bioconjugation & Probe Development: The primary amine group enables covalent attachment to proteins, surfaces, or other molecules for creating labeled probes for detection and purification.
• Diagnostic Assay Development: Serves as a key component in the design of high-sensitivity assays for clinical diagnostics and pharmaceutical screening.
• Metabolic Research: Applied in studies of cellular metabolism and redox biology to trace or modulate NAD-related pathways.
• Pharmaceutical Research: Investigated as a potential precursor or intermediate in the development of novel therapeutics targeting NAD metabolism.
• Material Science: Used for functionalizing surfaces in biosensor and biochip fabrication to enhance specificity and signal detection.

Basic Information

Product Name	2'-O-(N-(2-Aminoethyl)Carbamoylethyl)Phosphono-Nad
CAS No.	95754-66-8
Molecular Formula	C₂₀H₂₉N₇O₁₆P₂
Molecular Weight	685.44 g/mol
Synonyms	2'-O-[N-(2-Aminoethyl)carbamoylethyl]phosphono-NAD; Aminoethyl-Carbamoylethyl-Phosphono-NAD; NAD analog, aminoethyl functionalized; 2'-O-(2-((2-Aminoethyl)carbamoyl)ethyl)phosphono-NAD; Modified Nicotinamide Adenine Dinucleotide; Reactive NAD Derivative; CAS 95754-66-8
EINECS	Contact for details

Quality Control

Every batch of 2'-O-(N-(2-Aminoethyl)Carbamoylethyl)Phosphono-Nad is produced and tested under stringent quality management protocols. Our products undergo rigorous analytical testing, including HPLC and NMR, to ensure high purity and structural integrity, meeting the exacting standards required for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to moisture, heat, or light should be avoided to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.