Description

Intermedine n-Oxide is a pyrrolizidine alkaloid derivative, a compound of significant interest in advanced chemical research and development. Its unique oxidized structure makes it a valuable intermediate for synthesizing more complex molecules and studying specific biological pathways. This high-purity compound is primarily utilized by research institutions and pharmaceutical development laboratories focusing on natural product chemistry and toxicology studies.

Application

• Pharmaceutical Research Intermediate: Serves as a key building block in the synthesis and study of pyrrolizidine alkaloid analogs for pharmacological screening.
• Toxicology Reference Standard: Used as a certified reference material (CRM) in analytical laboratories to identify and quantify pyrrolizidine alkaloids and their metabolites in plant materials, food, and herbal products.
• Natural Product Chemistry: Employed in academic and industrial research to investigate the biosynthesis, chemical modification, and structure-activity relationships (SAR) of natural alkaloids.
• Analytical Method Development: Acts as a critical standard for developing and validating advanced analytical methods, such as LC-MS/MS, for the detection of hepatotoxic alkaloids in complex matrices.
• Biochemical Pathway Studies: Utilized in life science research to explore the metabolic activation and detoxification pathways of pyrrolizidine alkaloids.

Basic Information

Product Name	Intermedine n-Oxide
CAS No.	95462-14-9
Molecular Formula	C15H23NO6
Molecular Weight	313.35 g/mol
Synonyms	Intermedine N-Oxide; Intermedine Oxide; (+)-Intermedine N-Oxide; 7-(2-Methylbutyryl)retronecine N-oxide; 9-[(2S,3R)-3-Hydroxy-2-[(2S)-2-hydroxy-2-methylbutanoyl]oxy-6-(hydroxymethyl)-3,4,5,6-tetrahydro-2H-pyridin-1-yl]-6,7-dihydro-5H-pyrrolizine-1-carbaldehyde N-oxide; (1R,7aR)-1-[(2S)-2,3-Dihydroxy-2-methylbutanoyl]oxy-7-(hydroxymethyl)-2,3,5,7a-tetrahydro-1H-pyrrolizin-1-ium-6-carbaldehyde oxide
EINECS	Contact for details

Quality Control

Our Intermedine n-Oxide is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to relevant standards for high-purity reference materials to support your compliance and research integrity needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.