Description

1-Hexadecyl-2-Oleoyl-Sn-Glycero-3-Phosphorylcholine is a high-purity synthetic phospholipid, specifically a phosphatidylcholine (PC) derivative. This compound is a critical component for constructing advanced lipid-based delivery systems and biomimetic membranes. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require precise, reliable, and well-characterized lipid components for their formulations.

Application

• Liposome & Nanoparticle Formulation: A key structural lipid for creating stable, uniform liposomes and lipid nanoparticles (LNPs) for drug and gene delivery.
• Biomimetic Membrane Research: Used to create model cell membranes (e.g., supported lipid bilayers, vesicles) for studying membrane-protein interactions, permeability, and biophysical properties.
• Pharmaceutical Excipient: Serves as a functional excipient in injectable and topical formulations to enhance solubility, stability, and bioavailability of active pharmaceutical ingredients (APIs).
• Diagnostic Reagents: Incorporated into diagnostic kits and assays as a membrane component or signal carrier.
• Cosmetic Actives Carrier: Utilized in high-end cosmetic formulations for the targeted and sustained delivery of active compounds.
• Cell Culture & Cryopreservation: Acts as a supplement in specialized cell culture media and cryoprotectant solutions to maintain cell membrane integrity.

Basic Information

Product Name	1-Hexadecyl-2-Oleoyl-Sn-Glycero-3-Phosphorylcholine
CAS No.	95403-34-2
Molecular Formula	C42H84NO8P
Molecular Weight	762.09 g/mol
Synonyms	16:0-18:1 PC; 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC); (2R)-2-(Hexadecanoyloxy)-3-[(Z)-octadec-9-enoyloxy]propyl 2-(trimethylazaniumyl)ethyl phosphate; POPC (Phosphatidylcholine); 1-Cetyl-2-oleoyl-sn-glycero-3-phosphorylcholine; Phosphatidylcholine (16:0/18:1); 1-Hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
EINECS	Contact for details

Quality Control

Our 1-Hexadecyl-2-Oleoyl-Sn-Glycero-3-Phosphorylcholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, TLC for lipid profiling, and NMR for structural confirmation, to ensure it meets the stringent requirements for research and pharmaceutical applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and hydrolysis. For long-term storage, keep desiccated. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white waxy solid or powder
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Peroxide Value	< 3.0 meq/kg
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.