Description

Adenylyl Dihydrostreptomycin is a chemically modified derivative of the aminoglycoside antibiotic dihydrostreptomycin, where an adenylyl group is covalently attached. This modification is of significant interest in biochemical and pharmaceutical research, particularly for studying antibiotic resistance mechanisms and enzymatic modification pathways. It serves as a critical reference standard and intermediate for researchers and manufacturers in the fields of antibiotic development, molecular biology, and analytical chemistry.

Application

• Biochemical Research: Used as a substrate or reference compound in studies of aminoglycoside-modifying enzymes, particularly adenylyltransferases.
• Antibiotic Resistance Studies: Critical for investigating the molecular mechanisms of bacterial resistance to streptomycin-class antibiotics.
• Pharmaceutical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in antibiotic manufacturing.
• Enzymology Assays: Employed in in vitro assays to characterize enzyme kinetics and inhibition profiles.
• Intermediate Synthesis: Acts as a key synthetic intermediate for the preparation of other modified aminoglycoside derivatives for research purposes.

Basic Information

Product Name	Adenylyl Dihydrostreptomycin
CAS No.	95327-19-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Adenylyl-dihydrostreptomycin; Dihydrostreptomycin 3''-adenylylate; O3''-Adenylyldihydrostreptomycin; Dihydrostreptomycin adenylylated; Streptomycin 3''-adenylyltransferase substrate; Antibiotic resistance research compound; Modified aminoglycoside standard
EINECS	Contact for details

Quality Control

Our Adenylyl Dihydrostreptomycin is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research chemicals, ensuring reliable performance as a reference material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content	≤ 5.0%
Related Substances	Individual impurity ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.