Description

Teleocidin B-3 is a potent indole alkaloid belonging to the teleocidin family of protein kinase C (PKC) activators. This compound is of significant interest in biochemical and pharmacological research due to its role as a powerful tumor promoter and its ability to modulate cellular signaling pathways. It is primarily utilized by researchers in the fields of oncology, toxicology, and molecular biology for studying PKC-mediated processes, cancer mechanisms, and signal transduction. The compound is supplied with a high level of purity to ensure reliable and reproducible experimental results.

Application

• Biochemical Research: As a potent activator of Protein Kinase C (PKC) for studying enzyme kinetics, signal transduction cascades, and second messenger systems.
• Oncology & Cancer Research: Used as a tool compound to investigate tumor promotion mechanisms, cell proliferation, and apoptosis in various cancer cell lines.
• Pharmacology & Toxicology: Employed in studies examining the biological effects of tumor promoters and the structure-activity relationships of indole alkaloids.
• Neuroscience Research: Applied in research exploring the role of PKC in neuronal function, synaptic plasticity, and neurodegenerative diseases.
• Cell Biology Assays: Utilized as a reference standard or active agent in cell-based assays to induce specific cellular responses for mechanistic studies.
• Academic & Pharmaceutical R&D: Serves as a critical research chemical in university laboratories and pharmaceutical companies for drug discovery and target validation programs.

Basic Information

Item	Detail
Product Name	Teleocidin B-3
CAS No.	95189-06-3
Molecular Formula	C29H41N3O2
Molecular Weight	463.66 g/mol
Synonyms	Teleocidin B-3; (-)-Teleocidin B-3; Teleocidin B3; 95189-06-3; Lyngbyatoxin A congener; Indolactam V derivative; PKC activator teleocidin B-3
EINECS	Contact for details

Quality Control

Our Teleocidin B-3 is produced and handled under strict quality management protocols to ensure the highest standards of purity and consistency for research applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the exact specifications and test results for your quality assurance and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. The product is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, keep desiccated under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.