Description

2-Mercaptoethyl 2-(Acetylamino)-2-Deoxy-β-D-Galactopyranoside is a specialized thioglycoside derivative that serves as a critical building block in advanced biochemical synthesis. This compound matters for its unique combination of a reactive thiol group and a protected galactosamine moiety, enabling precise conjugation and modification strategies. It is primarily needed by research institutions and pharmaceutical developers working on targeted drug delivery systems, glycoprotein engineering, and the development of novel diagnostic probes and bioconjugates.

Application

• Bioconjugation & Linker Chemistry: Acts as a versatile heterobifunctional linker for attaching carbohydrates to proteins, peptides, or solid surfaces via thiol-maleimide or thiol-disulfide exchange chemistry.
• Glycobiology Research: Used as a key intermediate in the chemical and enzymatic synthesis of complex oligosaccharides, glycopeptides, and glycomimetics for structure-activity relationship studies.
• Pharmaceutical Development: Serves as a precursor in the synthesis of targeted therapeutics, including antibody-drug conjugates (ADCs) and carbohydrate-based vaccines, where site-specific glycosylation is crucial.
• Diagnostic Probe Synthesis: Employed in the creation of fluorescent or affinity-labeled carbohydrate probes for studying carbohydrate-protein interactions, such as lectin binding assays.
• Material Science & Surface Functionalization: Utilized to introduce carbohydrate epitopes onto nanoparticles, biosensors, or chromatography resins to create bioactive surfaces.
• Enzyme Substrate & Inhibitor Design: Functions as a substrate analog or inhibitor for glycosidases and glycosyltransferases in mechanistic enzymology studies.

Basic Information

Product Name	2-Mercaptoethyl 2-(Acetylamino)-2-Deoxy-β-D-Galactopyranoside
CAS No.	95074-13-8
Molecular Formula	C10H19NO6S
Molecular Weight	281.33 g/mol
Synonyms	2-(Acetylamino)-2-deoxy-β-D-galactopyranosyl 2-mercaptoethyl ether; 2-Acetamido-2-deoxy-β-D-galactopyranosyl 2-mercaptoethyl ether; N-Acetyl-β-D-galactosaminyl 2-mercaptoethyl ether; Thiogalactosamine derivative; 2-Mercaptoethyl β-D-GalNAc; S-2-Hydroxyethyl 2-acetamido-2-deoxy-1-thio-β-D-galactopyranoside; 1-Thio-β-D-GalNAc-(1→O)-CH2CH2SH
EINECS	Contact for details

Quality Control

Our 2-Mercaptoethyl 2-(Acetylamino)-2-Deoxy-β-D-Galactopyranoside is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store the product at -20°C under an inert atmosphere (e.g., argon or nitrogen) due to its sensitivity to oxidation. The container should be kept in a cool, dry, and well-ventilated area. Allow the product to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content	≤ 2.0%
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.