Description

Teleocidin B-1 is a potent indole alkaloid and a member of the teleocidin family of protein kinase C (PKC) activators. This compound is of significant interest in biochemical and pharmacological research due to its role as a powerful tumor promoter and its ability to modulate cellular signaling pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in cancer biology, signal transduction studies, and the development of novel therapeutic agents. The product is supplied with a high level of purity to ensure reliable and reproducible experimental results.

Application

• Biochemical Research: Used as a potent activator of Protein Kinase C (PKC) in studies of cell signaling, differentiation, and proliferation.
• Cancer Biology Studies: Employed as a classical tumor promoter in research models to investigate carcinogenesis and tumor progression mechanisms.
• Neuroscience Research: Applied in studies examining PKC's role in neurotransmitter release, synaptic plasticity, and neuronal function.
• Pharmacological Screening: Serves as a reference standard and tool compound in high-throughput screening for PKC inhibitors or modulators.
• Toxicology Studies: Used to investigate the mechanisms of action of tumor-promoting agents and their effects on cellular metabolism.
• Academic & Institutional Research: A key reagent for universities and research institutes focusing on molecular biology and chemical biology.

Basic Information

Product Name	Teleocidin B-1
CAS No.	95044-71-6
Molecular Formula	C29H41N3O2
Molecular Weight	463.66 g/mol
Synonyms	Teleocidin B-1; Lyngbyatoxin A; (-)-Teleocidin B-1; Teleocidin B1; 95044-71-6; Teleocidin B; 3,12-Didehydro-6-hydroxy-7,22-dioxo-8,20-epoxy-7,20-seco-7,8,9,10,11,12,19,20,21,22-decahydro-19,21-etheno-19-aza-21-carbacyclooctadecino[2,1-b]indole
EINECS	Contact for details

Quality Control

Our Teleocidin B-1 is produced under stringent quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your research integrity and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.