Description

C18 L-Threo Ceramide (D18:1/18:0) CAS NO 95037-06-2 is a high-purity, synthetic sphingolipid belonging to the ceramide family, characterized by its specific L-threo stereochemistry and defined acyl chain length. This compound is a critical building block for advanced lipid research and the formulation of high-performance cosmetic and pharmaceutical products, where its structural integrity directly influences biological activity and stability. It is primarily sought by R&D laboratories, manufacturers of premium skincare, and developers of lipid-based drug delivery systems who require a reliable, well-characterized standard and active ingredient.

Application

• Biomedical Research: As a key standard or reagent in studies of sphingolipid metabolism, cell signaling, apoptosis, and skin barrier function.
• Cosmetic & Skincare Formulations: A premium active ingredient in anti-aging, moisturizing, and skin barrier repair serums, creams, and lotions.
• Pharmaceutical Development: Used in the research and development of lipid-based drug delivery systems, such as liposomes and nanoemulsions.
• Analytical Reference Standard: For use in HPLC, LC-MS, and other analytical methods to quantify ceramides in complex biological or product matrices.
• Biochemical Synthesis: Serving as a precursor or intermediate in the enzymatic or chemical synthesis of more complex glycosphingolipids.
• Cell Culture & Tissue Engineering: Supplementation in media to study lipid raft formation or to create biomimetic membranes.

Basic Information

Product Name	C18 L-Threo Ceramide (D18:1/18:0)
CAS No.	95037-06-2
Molecular Formula	C36H71NO3
Molecular Weight	565.97 g/mol
Synonyms	N-Octadecanoyl-D-erythro-sphingosine; N-Stearoyl-D-erythro-sphingosine; N-(Octadecanoyl)-sphing-4-enine; Ceramide (d18:1/18:0); Ceramide NS; Ceramide 2; L-threo-1,3-Dihydroxy-2-octadecylamino-4-trans-octadecene; N-(1,3-Dihydroxyoctadec-4-en-2-yl)octadecanamide
EINECS	Contact for details

Quality Control

Our C18 L-Threo Ceramide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets exacting standards for research and formulation use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Assay	95.0 - 102.0%
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.