Description

Ec 3.4.22.38 CAS NO 94716-09-3 is a high-purity enzyme belonging to the cysteine protease family, specifically a caspase. This product is essential for researchers and developers in life sciences, providing a critical tool for studying programmed cell death (apoptosis) and related biochemical pathways. It is primarily utilized in pharmaceutical R&D, diagnostic assay development, and biochemical research where precise enzymatic activity is required.

Application

• Biochemical Research: A key reagent for in vitro studies of apoptosis signaling cascades and protease activity assays.
• Pharmaceutical Development: Used in drug discovery platforms to screen and evaluate potential therapeutic compounds targeting caspase-mediated pathways.
• Diagnostic Manufacturing: Incorporated into enzyme-based assay kits for the detection of apoptotic markers in clinical and research samples.
• Cell Biology Studies: Employed to induce or inhibit apoptosis in cell culture models to study cellular mechanisms and disease pathology.
• Protein Analysis: Serves as a specific protease for protein cleavage and processing in structural and functional proteomics.

Basic Information

Product Name	Ec 3.4.22.38
CAS No.	94716-09-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Caspase-1; Interleukin-1β Converting Enzyme (ICE); IL-1β-Converting Enzyme; CASP1; P45; EC 3.4.22.36 (Note: Often grouped with 3.4.22.38); Apoptosis-Related Cysteine Protease; Cysteine protease caspase 1
EINECS	Contact for details

Quality Control

Our Ec 3.4.22.38 is produced and tested under stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity, specific activity, and functional consistency. Certificates of Analysis (COA) documenting purity (by HPLC/SDS-PAGE), activity (by fluorometric or colorimetric assay), and absence of contaminating proteases are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a non-frost-free freezer. The product is hygroscopic (moisture-sensitive). For long-term storage, consider under inert atmosphere. Aliquot to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Activity)	Conforms (Specific activity ≥ XX units/mg protein)
Purity (SDS-PAGE)	≥ 90%
Protein Content (Bradford)	≥ XX %
Specific Activity	≥ XX units/mg
Endotoxin (LAL)	< 1.0 EU/μg
Solubility	Soluble in appropriate assay buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.