Description

Lecithin-Retinol Acyltransferase CAS NO 117444-03-8 is a critical enzyme involved in the retinoid cycle, specifically catalyzing the transfer of fatty acyl groups to retinol. This biochemical function is essential for the visual process and cellular signaling pathways related to vitamin A metabolism. It is a vital reagent for researchers and developers in the fields of biochemistry, ophthalmology, and pharmaceutical development, particularly for studies on retinal diseases, vitamin A metabolism, and enzyme kinetics.

Application

• Biochemical Research: Used as a key enzyme in studies investigating the retinoid visual cycle and retinol metabolism pathways.
• Pharmaceutical Development: Serves as a target or reagent in drug discovery programs focused on treating retinal degenerative diseases.
• Diagnostic Assay Development: Employed in the development of enzymatic assays to measure LRAT activity in biological samples for research and potential clinical diagnostics.
• Enzymology Studies: Utilized for kinetic analysis, inhibitor screening, and understanding structure-function relationships of acyltransferases.
• Cell Biology & Nutrition Research: Applied in cellular models to study the role of vitamin A esterification in cell differentiation, vision, and immune function.

Basic Information

Product Name	Lecithin-Retinol Acyltransferase
CAS No.	117444-03-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	LRAT; Lecithin Retinol Acyltransferase; Retinol Acyltransferase; Acyl-CoA Retinol Acyltransferase; Phosphatidylcholine-Retinol O-Acyltransferase; EC 2.3.1.135; Retinol Fatty-Acyltransferase
EINECS	Contact for details

Quality Control

Our Lecithin-Retinol Acyltransferase is produced and handled under stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity, specific activity, and functional integrity. Certificates of Analysis (COA) detailing purity, activity units, and stability data are available upon request to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Avoid repeated freeze-thaw cycles to maintain optimal enzymatic activity.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Purity (SDS-PAGE)	≥ 90%
Specific Activity	Contact for details
Protein Concentration	Contact for details
Identification (Activity)	Conforms
Endotoxin Level	< 1.0 EU/µg (if applicable)
Buffer Composition	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.