Description

Dolichyl Dolichoate is a naturally occurring glycolipid derivative involved in the biosynthesis of N-linked glycoproteins, serving as a critical lipid carrier for oligosaccharide assembly in the endoplasmic reticulum. Its precise structural fidelity and functional integrity are essential for reproducible glycosylation studies and biopharmaceutical process development. Researchers and manufacturers in glycobiology, recombinant protein therapeutics, and cell culture media formulation rely on high-purity Dolichyl Dolichoate CAS NO 94555-72-3 to ensure experimental consistency and regulatory compliance.

Application

• Glycoprotein biosynthesis research — as a substrate for dolichol-linked oligosaccharide transfer assays
• Cell-free glycosylation systems for synthetic biology and enzymatic glycoengineering
• Development and optimization of CHO and HEK293 cell culture media for monoclonal antibody production
• Reference standard in LC-MS and HPTLC-based analysis of dolichol phosphate metabolism
• Investigation of congenital disorders of glycosylation (CDG) pathophysiology and therapeutic screening
• Stabilization and functional reconstitution of oligosaccharyltransferase (OST) complexes
• Preparation of radiolabeled or fluorescently tagged dolichol analogs for trafficking studies
• Quality control testing of glycosylation efficiency in biomanufacturing processes

Basic Information

Product Name	Dolichyl Dolichoate
CAS No.	94555-72-3
Molecular Formula	C105H172O8
Molecular Weight	1622.5 g/mol (approx., varies with dolichol chain length distribution)
Synonyms	Dolichyl ester of dolicholic acid; Dolichyl dolichate; Dolichyl dolicol ester; Dolichyl 3,5-cyclohexadiene-1-carboxylate; Dolichyl cyclohexadienecarboxylate; Dolichyl ester of α-dolicholic acid; Dolichyl dolichoate (mixture); Dolichyl ester of dolichol acid
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. Each batch is verified for identity (IR, HPLC retention time), purity (≥95% by HPLC), and absence of critical impurities including free dolichol and oxidized derivatives. Testing aligns with best practices for lipid-based biochemical reagents used in GMP-aligned research environments.

Storage

Preserve in a tightly closed container, protected from light. Store under inert atmosphere (argon or nitrogen) at –20 °C. Avoid repeated freeze-thaw cycles. Keep desiccated; sensitive to moisture and oxidation.

Specification

Item	Specification
Appearance	Pale yellow to off-white viscous oil or amorphous solid
Identification (IR)	Conforms to reference spectrum (characteristic ester C=O stretch at ~1735 cm⁻¹; dolichol backbone absorptions)
Assay (HPLC)	≥95.0%
Related Substances (HPLC)	Free dolichol ≤ 2.0%; Oxidized derivatives ≤ 1.5%
Residue on Ignition	≤ 0.1%
Water (KF)	≤ 0.2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.