Description

1,4,7-Tritosyl-1,4,7,10-Tetraazacyclododecane is a key functionalized macrocyclic ligand, widely recognized for its role as a versatile precursor in coordination chemistry. Its primary value lies in its ability to chelate metal ions, forming stable complexes that are fundamental to advanced research and industrial catalysis. This compound is essential for researchers and manufacturers in the fields of magnetic resonance imaging (MRI) contrast agent development, radiopharmaceuticals, and homogeneous catalysis.

Application

• Precursor for MRI Contrast Agents: Serves as a critical intermediate in the synthesis of gadolinium-based macrocyclic complexes used in diagnostic imaging.
• Radiopharmaceutical Synthesis: Used in the development of chelators for radiolabeling with isotopes like 64Cu, 68Ga, and 177Lu for targeted cancer therapy and diagnostics.
• Homogeneous Catalysis: Acts as a ligand scaffold for creating transition metal catalysts used in organic synthesis and polymerization reactions.
• Chemical Research & Development: A fundamental building block in supramolecular chemistry and for studying metal-ligand interaction kinetics.
• Sensor Technology: Employed in the design of luminescent or electrochemical sensors for metal ion detection.

Basic Information

Product Name	1,4,7-Tritosyl-1,4,7,10-Tetraazacyclododecane
CAS No.	94530-07-1
Molecular Formula	C39H51N4O6S3
Molecular Weight	768.02 g/mol
Synonyms	1,4,7-Tris(p-toluenesulfonyl)-1,4,7,10-tetraazacyclododecane; 1,4,7-Tris(4-methylbenzenesulfonyl)-1,4,7,10-tetraazacyclododecane; Tritosyl-DOTA; Tritosyl cyclen; 1,4,7-Tris(tosyl)-1,4,7,10-tetraazacyclododecane; DOTA-tris(tosylate); 1,4,7-Tris-O-tosyl-1,4,7,10-tetraazacyclododecane
EINECS	Contact for details

Quality Control

Our 1,4,7-Tritosyl-1,4,7,10-Tetraazacyclododecane is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistent performance for sensitive applications like pharmaceutical intermediate synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.