Description

4-Hydrazinocarbonylpyridine-1,N(6)-Ethenoadenine Dinucleotide is a chemically modified dinucleotide analog, a key intermediate in the synthesis of advanced biochemical probes and research reagents. This compound is valued for its role in developing affinity labels and mechanism-based inhibitors for enzymes that interact with natural dinucleotides like NAD(P)H. It is primarily sought by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in enzymology, metabolic pathway studies, and the development of novel diagnostic tools.

Application

• Biochemical Research: As a critical intermediate for synthesizing affinity-labeling reagents targeting NAD(P)H-dependent enzymes.
• Enzyme Inhibitor Development: Used in the design and synthesis of mechanism-based (suicide) inhibitors for dehydrogenase and reductase enzymes.
• Diagnostic Probe Synthesis: Serves as a precursor for creating fluorescent or radioactive probes to study enzyme kinetics and localization.
• Pharmaceutical R&D: Employed in early-stage drug discovery programs targeting metabolic disorders and cancers linked to specific dehydrogenase activity.
• Academic Research: Utilized in universities and research institutes for fundamental studies on nucleotide-protein interactions and redox biology.

Basic Information

Product Name	4-Hydrazinocarbonylpyridine-1,N(6)-Ethenoadenine Dinucleotide
CAS No.	94516-26-4
Molecular Formula	C₂₂H₂₄N₁₀O₁₂P₂
Molecular Weight	706.46 g/mol
Synonyms	1,N(6)-Etheno-NAD+ hydrazide; Etheno-NAD+ hydrazide; 4-Hydrazinocarbonylpyridine-1,N6-ethenoadenine dinucleotide; 1,N6-Ethenonicotinamide adenine dinucleotide hydrazide; Modified NAD+ analog; NAD+ etheno-derivative hydrazide; Research biochemical intermediate
EINECS	Contact for details

Quality Control

Our 4-Hydrazinocarbonylpyridine-1,N(6)-Ethenoadenine Dinucleotide is produced under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store in a cool, dry place, ideally at 2-8°C for long-term stability. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.