Description

n-Nervonoyl-D-Erythro-Sphingosylphosphorylcholine is a highly defined, synthetic sphingolipid derivative, specifically a nervonoyl-ceramide-1-phosphate. This compound is a critical research-grade biochemical tool for investigating lipid signaling pathways, membrane biophysics, and cellular processes. It is essential for scientists and product developers in pharmaceutical R&D, advanced cosmetics, and lipidomics research who require high-purity, structurally precise lipids to ensure experimental reproducibility and product efficacy.

Application

• Biomedical Research: As a key standard and substrate for studying enzymes like ceramide kinase and sphingomyelin synthases in signal transduction related to apoptosis, inflammation, and cell proliferation.
• Lipidomics & Analytical Standards: Used as a high-purity internal standard or reference compound in mass spectrometry (LC-MS/MS) for the accurate quantification of complex sphingolipids in biological samples.
• Drug Discovery & Development: Employed in target validation, high-throughput screening assays, and formulation studies for novel therapeutics targeting lipid metabolism disorders.
• Cosmeceutical R&D: Investigated for its potential role in skin barrier function and as a bioactive ingredient in premium skincare formulations aimed at skin repair and moisturization.
• Biophysical Studies: Utilized in model membrane systems (e.g., liposomes, lipid bilayers) to study the effects of specific ceramide phosphates on membrane structure, curvature, and permeability.
• Cell Culture & Neuroscience: Applied in specialized cell culture media or as an exogenous agent to study its effects on neuronal differentiation, survival, and myelination processes.

Basic Information

Item	Detail
Product Name	n-Nervonoyl-D-Erythro-Sphingosylphosphorylcholine
CAS No.	94359-13-4
Molecular Formula	C52H101N2O9P
Molecular Weight	929.34 g/mol
Synonyms	Nervonoyl Ceramide-1-Phosphate; N-Nervonoyl-D-erythro-sphingosylphosphorylcholine; (2S,3R,4E)-2-[(R)-2-Hydroxytetracosanoylamino]-4-octadecene-1,3-diol 1-(Dihydrogen Phosphate) 2-(Trimethylammonio)ethyl Ester; Ceramide-1-phosphate (C24:1, nervonic acid); C24:1 Ceramide-1-Phosphate; D-erythro-Ceramide-1-phosphate (nervonoyl); Sphingomyelin analogue (nervonoyl); Lyso-N-nervonoyl-sphingosylphosphocholine
EINECS	Contact for details

Quality Control

Every batch of our n-Nervonoyl-D-Erythro-Sphingosylphosphorylcholine is produced and analyzed under strict quality management protocols. We employ advanced chromatographic and spectroscopic techniques to ensure structural identity and high chemical purity, typically exceeding 95% (by HPLC). A comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profile is provided with each shipment to support your research integrity and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid (lyophilized powder or film)
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 2.0%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.