Description

2'-Deoxyuridine 5'-Triphosphate Sodium Salt is a modified nucleotide triphosphate essential for advanced molecular biology and diagnostic applications. Its core value lies in its role as a substrate for DNA polymerases, enabling precise control in enzymatic synthesis and sequencing workflows. This high-purity biochemical is critically needed by researchers and manufacturers in the pharmaceutical, biotechnology, and in-vitro diagnostics (IVD) industries for applications such as PCR, next-generation sequencing (NGS), and probe synthesis.

Application

• Molecular Biology Research: As a substrate (dUTP) for DNA polymerases in enzymatic DNA synthesis, PCR, and site-directed mutagenesis.
• Next-Generation Sequencing (NGS): A key component in sequencing-by-synthesis (SBS) platforms and library preparation kits.
• Diagnostic Assay Development: Used in the manufacturing of probes and primers for clinical diagnostics, including real-time PCR (qPCR) assays.
• Biochemical Studies: Employed in enzymatic assays to study DNA replication, repair mechanisms, and polymerase kinetics.
• Antiviral Drug Research: Serves as a reference compound or precursor in the development and screening of nucleoside analog-based therapeutics.
• Labeling and Detection: Can be modified or used as a backbone for incorporating labels (e.g., fluorescent, biotin) into nucleic acids.

Basic Information

Product Name	2'-Deoxyuridine 5'-Triphosphate Sodium Salt
CAS No.	94234-60-3
Molecular Formula	C9H13N2Na3O14P3 (or similar salt form)
Molecular Weight	Contact for details
Synonyms	dUTP Sodium Salt; 2'-Deoxyuridine-5'-triphosphate trisodium salt; Deoxyuridine triphosphate sodium; dUTP, Na salt; 5'-dUTP; Deoxyuridine 5'-(tetrahydrogen triphosphate), trisodium salt; Uracil deoxyribonucleoside triphosphate sodium salt
EINECS	Contact for details

Quality Control

Our 2'-Deoxyuridine 5'-Triphosphate Sodium Salt is manufactured under stringent quality systems to ensure batch-to-batch consistency suitable for sensitive research and diagnostic applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, spectroscopy for identification, and tests for moisture and endotoxin levels where required. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under inert atmosphere to maintain stability. Allow the product to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/UV)	Conforms
Purity (HPLC)	≥ 95% (Typical ≥98%)
Assay (Enzymatic)	≥ 90%
Water Content (KF)	≤ 5.0%
pH (Solution)	6.0 - 8.0
Endotoxin (LAL)	< 10 EU/mg (if applicable)
Solubility	Soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.