Description

11Beta,17,21-Trihydroxy-6Alpha-Methylpregna-1,4-Diene-3,20-Dione 21-Acetylsalicylate is a high-purity synthetic steroid derivative, specifically an ester of a glucocorticoid. This compound is of significant value in pharmaceutical research and development due to its potential as a key intermediate or active pharmaceutical ingredient (API) for anti-inflammatory and immunosuppressive therapies. It is primarily needed by pharmaceutical manufacturers, R&D laboratories, and fine chemical suppliers engaged in the synthesis of advanced corticosteroid medications.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of potent glucocorticoid drugs.
• Anti-inflammatory Drug Research: Used in preclinical and clinical research for developing new topical and systemic anti-inflammatory agents.
• Immunosuppressant Development: Investigated for its potential in creating medications to manage autoimmune diseases and prevent organ transplant rejection.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Biochemical Research: Utilized in studies exploring glucocorticoid receptor binding and steroid hormone metabolism pathways.
• Veterinary Pharmaceutical Synthesis: Applied in the development of anti-inflammatory treatments for animal health.

Basic Information

Product Name	11Beta,17,21-Trihydroxy-6Alpha-Methylpregna-1,4-Diene-3,20-Dione 21-Acetylsalicylate
CAS No.	94135-36-1
Molecular Formula	C31H38O8
Molecular Weight	538.63 g/mol
Synonyms	6α-Methylprednisolone 21-Acetylsalicylate; Methylprednisolone Acefurate; Acefurate de Méthylprednisolone; 6α-Methyl-11β,17α,21-trihydroxypregna-1,4-diene-3,20-dione 21-(2-acetoxybenzoate); Prednisolone Derivative CAS 94135-36-1; 6-Methyl-δ1-cortisol 21-acetylsalicylate; Glucocorticoid Ester Intermediate
EINECS	Contact for details

Quality Control

Our 11Beta,17,21-Trihydroxy-6Alpha-Methylpregna-1,4-Diene-3,20-Dione 21-Acetylsalicylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade pharmaceutical standards. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.