Description

Lithium 3,7,12-Trioxo-5Beta-Cholan-24-Oate is a high-purity lithium salt of a modified bile acid derivative, serving as a critical intermediate in advanced pharmaceutical synthesis. This compound is valued for its specific molecular structure, which is essential for research and development in targeted therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on metabolic and liver-related drug discovery.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel steroidal drugs and bile acid analogs.
• Biochemical Research: Used as a reference standard or reagent in metabolic pathway studies and enzyme inhibition assays.
• Drug Discovery: Serves as a precursor for developing potential therapeutics targeting nuclear receptors like FXR (Farnesoid X Receptor).
• Fine Chemical Synthesis: Intermediate for producing more complex, high-value cholanic acid derivatives with specific biological activities.

Basic Information

Product Name	Lithium 3,7,12-Trioxo-5Beta-Cholan-24-Oate
CAS No.	94107-86-5
Molecular Formula	C24H33LiO6
Molecular Weight	424.46 g/mol
Synonyms	Lithium 3,7,12-trioxo-5β-cholan-24-oate; Lithocholic acid derivative lithium salt; 5β-Cholan-24-oic acid, 3,7,12-trioxo-, lithium salt; 3,7,12-Trioxolithocholic acid lithium salt; 3α-Hydroxy-7,12-dioxo-5β-cholan-24-oic acid lithium salt (related); Chenodeoxycholic acid derivative lithium salt; 7,12-Dihydroxy-3-oxo-5β-cholan-24-oic acid lithium salt (related); Bile acid lithium salt intermediate
EINECS	Contact for details

Quality Control

Our Lithium 3,7,12-Trioxo-5Beta-Cholan-24-Oate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.