Description

Doxycycline Calcium is a calcium salt derivative of the broad-spectrum tetracycline antibiotic, doxycycline. This formulation is primarily utilized in veterinary medicine and animal husbandry for its enhanced stability and bioavailability. Key industries requiring this compound include pharmaceutical manufacturing for veterinary products, animal feed additive production, and aquaculture. It is supplied as a high-purity active pharmaceutical ingredient (API) suitable for formulation.

Application

• Veterinary Pharmaceutical Formulations: Used as an active ingredient in oral suspensions, powders, and premixes for the treatment of bacterial infections in livestock, poultry, and companion animals.
• Animal Feed Additive: Incorporated into medicated feeds for growth promotion and disease prevention in swine, poultry, and cattle.
• Aquaculture: Applied for the control of bacterial diseases in farmed fish and shrimp.
• Poultry Health Management: Effective against respiratory and enteric diseases in chickens and turkeys.
• Swine Industry: Used for the prevention and treatment of conditions like atrophic rhinitis and swine dysentery.
• Companion Animal Medicine: Formulated into medications for dogs and cats for treating various infections.

Basic Information

Product Name	Doxycycline Calcium
CAS No.	94088-85-4
Molecular Formula	C44H62CaN2O18
Molecular Weight	923.04 g/mol
Synonyms	Doxycycline Calcium Salt; Doxycycline Calcium Complex; Doxycycline Hemicalcium; Vibramycin Calcium; 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide Calcium Salt; GS 3065 (Calcium); α-6-Deoxyoxytetracycline Calcium
EINECS	Contact for details

Quality Control

Our Doxycycline Calcium is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. Certificates of Analysis (COA) documenting parameters such as assay, related substances, and residual solvents are provided with every shipment. We adhere to cGMP principles and can support compliance with major pharmacopoeial standards (e.g., USP, EP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light yellow powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Conforms to standard
Assay (HPLC)	95.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any individual impurity ≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines
Microbial Enumeration	Meets standard limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.