Description

3-(Phosphonooxy)-1,2-Propanediyl Bis[(9Z,12Z,15Z)-9,12,15-Octadecatrienoate] is a specialized phospholipid derivative, a key intermediate in the synthesis of advanced lipid-based delivery systems. Its molecular structure, incorporating a phosphonooxy group and multiple unsaturated fatty acid chains, makes it a valuable precursor for creating functional biomaterials with targeted properties. This compound is essential for research and development in the pharmaceutical and nutraceutical industries, particularly for formulating liposomes, lipid nanoparticles, and other advanced drug delivery vehicles. The CAS number for this compound is 94086-57-4.

Application

• Pharmaceutical Excipient: A critical intermediate for synthesizing phospholipid-based drug delivery systems, including liposomes and solid lipid nanoparticles (SLNs) for improved drug solubility and bioavailability.
• Nutraceutical Formulations: Used in the development of advanced lipid carriers for fat-soluble vitamins (A, D, E, K) and ω-3 fatty acid supplements to enhance stability and absorption.
• Biomaterial Research: Serves as a building block for creating functionalized lipid membranes and vesicles in biophysical studies and diagnostic assay development.
• Cosmetic Actives Carrier: Employed in high-end cosmetic formulations to create nano-encapsulation systems for active ingredients, promoting deeper skin penetration and sustained release.
• Chemical Synthesis: Acts as a versatile phosphorylated intermediate for the organic synthesis of more complex glycerophospholipids and signaling molecules.

Basic Information

Product Name	3-(Phosphonooxy)-1,2-Propanediyl Bis[(9Z,12Z,15Z)-9,12,15-Octadecatrienoate]
CAS No.	94086-57-4
Molecular Formula	C₃₉H₆₅O₈P
Molecular Weight	692.90 g/mol
Synonyms	1,2-Di-α-linolenoyl-3-phosphoglycerol; Glycerol 3-phosphate di-α-linolenate; 1,2-Bis(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphoric acid; Phosphatidic acid di-α-linolenate; PA(18:3/18:3); 1,2-Dilinolenoylphosphatidic acid; sn-Glycerol-3-phosphoric acid 1,2-dilinolenate
EINECS	Contact for details

Quality Control

Our production of 3-(Phosphonooxy)-1,2-Propanediyl Bis[(9Z,12Z,15Z)-9,12,15-Octadecatrienoate] adheres to stringent quality protocols suitable for research and pharmaceutical intermediate applications. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, related substances, and residual solvents are provided and available upon request. Our quality management system supports compliance with cGMP and ISO 9001 standards for reliable supply.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at -20°C or below to minimize oxidation and hydrolysis. For long-term stability, the material should be kept in a desiccated environment. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	Yellow to amber viscous liquid or semi-solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Peroxide Value	≤ 10.0 mEq/kg
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.